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Предходни/ Резултат

Предходни/ Резултат

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

 
C16-(branched), C20-(branched) and C24-(branched)-alkanes 700-992-1 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
28/02/2018
28/02/2018
28/02/2018
16/04/2018
16/04/2018
16/04/2018
Link
4-tert-butylpyrocatechol 202-653-9 98-29-3
Reproductive toxicity (extended one-generation reproductive toxicity study)
Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant.
28/02/2018
28/02/2018
16/04/2018
16/04/2018
Link
ethyl methyl carbonate 433-480-9 -
Sub-chronic toxicity (90-day): oral || Note: testing proposed with an analogue substance.
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with an analogue substance.
28/02/2018
28/02/2018
16/04/2018
16/04/2018
Link
Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine 500-191-5 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
28/02/2018
28/02/2018
16/04/2018
16/04/2018
Link
Fatty acids, C18-unsatd., dimers, polymers with oleic acid and triethylenetetramine 701-120-2 -
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine
28/02/2018
28/02/2018
16/04/2018
16/04/2018
Link
Fatty acids, C18-unsatd., dimers, reaction products with polyethylenepolyamines 614-452-7 68410-23-1
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine
28/02/2018
28/02/2018
16/04/2018
16/04/2018
Link
Polysulfides, bis[3-(triethoxysilyl)propyl] 915-673-4 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
28/02/2018
28/02/2018
16/04/2018
16/04/2018
Link
Triethoxy(2,4,4-trimethylpentyl)silane 252-558-1 35435-21-3
Long-term toxicity to fish || Note: Testing on fish needs to be considered in relation to the testing proposal for long-term toxicity to aquatic invertebrates.
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with triethoxyoctylsilane (CAS 2943-75-1)
28/02/2018
28/02/2018
16/04/2018
16/04/2018
Link
2-Butyne-1,4-diol, polymer with 2-(chloromethyl)oxirane, brominated, dehydrochlorinated, methoxylateddehydrochlorinated, methoxylated 614-503-3 68441-62-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018 Link
Alkenes, C11-12, hydroformylation products, distn. Residues 292-427-6 90622-27-8 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018 Link
Aluminium oxide 215-691-6 1344-28-1 Genetic toxicity in vivo || Note: Testing proposal for two in vivo studies is based on concern identified by the registrant. Testing proposed with Aluminium oxide nanoscale material. 28/02/2018 16/04/2018 Link
Bis(4-chlorophenyl) sulphone 201-247-9 80-07-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018 Link
Calcium cyanamide 205-861-8 156-62-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018 Link
Citral 226-394-6 5392-40-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018 Link
Dihydrogen hexahydroxyplatinate 257-471-2 51850-20-5 Genetic toxicity in vivo || Note: Testing proposed with dihydrogen hexahydroxyplatinate(IV), compound with 2-aminoethanol (1:2). Testing proposal is based on concern identified by the registrant. 28/02/2018 16/04/2018 Link
Dimethylamine 204-697-4 124-40-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018 Link
Fatty acids, tall-oil, compds. with N-[3-(dimethylamino)propyl]tall-oil amides 295-714-4 92128-22-8 Reproductive toxicity (pre-natal developmental toxicity) 28/02/2018 16/04/2018 Link
Hexahydro-4-methylphthalic anhydride 243-072-0 19438-60-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018 Link
Reaction products of di-, tri- and tetra-propoxylated propane-1,2-diol with ammonia 618-561-0 - Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018 Link
Tetraammineplatinum dichloride 237-706-5 13933-32-9 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 28/02/2018 16/04/2018 Link
Tetraammineplatinum dinitrate 243-929-9 20634-12-2 Genetic toxicity in vivo || Note: testing proposed with tetraammineplatinum(II) dichloride. Testing proposal is based on concern identified by the registrant. 28/02/2018 16/04/2018 Link
Vinyl neononanoate 259-160-7 54423-67-5 Reproductive toxicity (extended one-generation reproductive toxicity study) 28/02/2018 16/04/2018 Link
Polysulfides, di-tert-dodecyl 270-335-7 68425-15-0
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
31/01/2018
31/01/2018
31/01/2018
19/03/2018
19/03/2018
19/03/2018
Link
2,4,6,8,10-pentamethylcyclopentasiloxane 228-204-7 6166-86-5
Sub-chronic toxicity (90-day): oral || Note: testing proposed with 2,4,6,8-tetramethylcyclotetrasiloxane (CAS 2370-88-9; EC 219-137-4; HD4)
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2,4,6,8-tetramethylcyclotetrasiloxane (CAS 2370-88-9; EC 219-137-4; HD4)
31/01/2018
31/01/2018
19/03/2018
19/03/2018
Link

2-(4-fluorophenyl)-5-(5-iodo-2-methylbenzyl)thiophene 618-312-6 898566-17-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
31/01/2018
31/01/2018
19/03/2018
19/03/2018
Link
[[(phosphonomethyl)imino]bis[hexamethylenenitrilobis(methylene)]]tetrakisphosphonic acid 252-156-6 34690-00-1
Sub-chronic toxicity (90-day): oral || Note: testing proposed with either the registered substance or a read-across substance, which would be a salt of the same phosphonic acid; or salt of a structurally analogous phosphonic acid, HMDTMP
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with either the registered substance or a read-across substance, which would be a salt of the same phosphonic acid; or salt of a structurally analogous phosphonic acid, HMDTMP
31/01/2018
31/01/2018
19/03/2018
19/03/2018
Link
Amines, polyethylenepoly-, tetraethylenepentamine fraction 292-587-7 90640-66-7
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with TETA (CAS 90640-67-8) and HEPA (68121-73-7)
Reproductive toxicity (pre-natal developmental toxicity )
31/01/2018
31/01/2018
19/03/2018
19/03/2018
Link
Ashes (residues), plant 297-049-5 93333-79-0
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
31/01/2018
31/01/2018
19/03/2018
19/03/2018
Link
Ditetradecyl peroxydicarbonate 258-436-4 53220-22-7
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity
31/01/2018
31/01/2018
19/03/2018
19/03/2018
Link
Potassium salts of {hexane-1,6-diylbis[nitrilobis(methylene)]}tetrakisphosphonic acid (4-7:1)  701-184-1 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
31/01/2018
31/01/2018
19/03/2018
19/03/2018
Link
Reaction products of pentaerythritol, propoxylated and 1-chloro-2,3-epoxypropane with hydrogen sulfide 701-196-7 -
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant.
Reproductive toxicity (pre-natal developmental toxicity)
31/01/2018
31/01/2018
19/03/2018
19/03/2018
Link
Biphenyl 202-163-5 92-52-4 Reproductive toxicity (pre-natal developmental toxicity) 31/01/2018 19/03/2018 Link
Everzol Red CDN Crude 483-940-8 - Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 31/01/2018 19/03/2018 Link
Octadecanoic acid, sulfonated, potassium salt 701-179-4 - Sub-chronic toxicity (90-day): oral || Note: The List number has changed. 31/01/2018 19/03/2018 Link
Pivalic acid 200-922-5 75-98-9
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
Reproductive toxicity (extended one-generation reproductive toxicity study)
20/12/2017
20/12/2017
20/12/2017
05/02/2018
05/02/2018
05/02/2018
Link
2-(2-Vinyloxyethoxy)ethyl acrylate 451-690-9 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
20/12/2017
20/12/2017
05/02/2018
05/02/2018
Link
pentaerythritol 204-104-9 115-77-5
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
20/12/2017
20/12/2017
05/02/2018
05/02/2018
Link
Isotridecan-1-ol 248-469-2 27458-92-0 Reproductive toxicity (pre-natal developmental toxicity) 20/12/2017 05/02/2018 Link
1,4-phenylene bis[(4-phenoxyphenyl)-methanone] 620-097-9 54299-17-1
Bioaccumulation aquatic / sediment
Long-term toxicity to fish
22/11/2017
22/11/2017
08/01/2018
08/01/2018
Link
2,4,6,8-tetramethylcyclotetrasiloxane 219-137-4 2370-88-9
Sub-chronic toxicity (90-day): oral
-
22/11/2017
22/11/2017
08/01/2018
08/01/2017
Link
3,6,9,12-tetraazatetradecamethylenediamine 223-775-9 4067-16-7
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with structural analogues TETA (CAS 90640-67-8) and HEPA (CAS 68121-73-7).
Reproductive toxicity (pre-natal developmental toxicity)
22/11/2017
22/11/2017
08/01/2018
08/01/2018
Link
a,a-dimethylphenethyl butyrate 233-221-8 10094-34-5
Sub-chronic toxicity (90-day): oral“|| Note: testing proposed 1,1-Dimethyl-2-phenylethyl acetate (EC 205-781-3)”
Reproductive toxicity (pre-natal developmental toxicity)“|| Note: testing proposed 1,1-Dimethyl-2-phenylethyl acetate (EC 205-781-3)”
22/11/2017
22/11/2017
08/01/2018
08/01/2018
Link
Amines, polyethylenepoly-, triethylenetetramine fraction 292-588-2 90640-66-7
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
22/11/2017
22/11/2017
08/01/2018
08/01/2018
Link

4-phenylbutan-2-one 219-847-4 2550-26-7 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with a read-across substance having similar formula structure and its carbon chain consists of even number of carbons 22/11/2017 08/01/2018 Link
Amines, polyethylenepoly- 268-626-9 68131-73-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 22/11/2017 08/01/2018 Link
Glycerol, propoxylated, esters with acrylic acid 500-114-5 52408-84-1 Sub-chronic toxicity (90-day): oral 22/11/2017 08/01/2018 Link
(-)-pin-2(3)-ene 232-077-3 7785-26-4 Reproductive toxicity (pre-natal developmental toxicity) 25/10/2017 11/12/2017 Link
2,2'-[hexane-1,6-diylbis(oxymethylene)]dioxirane 618-939-5 933999-84-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/10/2017 11/12/2017 Link
4'-hydroxyacetophenone 202-802-8 99-93-4 Reproductive toxicity (pre-natal developmental toxicity) 25/10/2017 11/12/2017 Link
Benzenamine, N-phenyl-, reaction products with 2,4,4-trimethylpentene 270-128-1 68411-46-1 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/10/2017 11/12/2017 Link



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