Substance Information

Substance information

Infocards are automatically generated based on industry data. What is an infocard?

Substance Infocard

IC

Epinephrine

Help Substance identity

The ‘Substance identity’ section is calculated from substance identification information from all ECHA databases. The substance identifiers displayed in the InfoCard are the best available substance name, EC number, CAS number and/or the molecular and structural formulas.

Some substance identifiers may have been claimed confidential, or may not have been provided, and therefore not be displayed.

EC (European Community) Number

The EC Number is the numerical identifier for substances in the EC Inventory. The EC Inventory is a combination of three independent European lists of substances from the previous EU chemicals regulatory frameworks (EINECS, ELINCS and the NLP-list). More information about the EC Inventory can be found here.

If the substance was not covered by the EC Inventory, ECHA attributes a list number in the same format, starting with the numbers 6, 7, 8 or 9.

The EC or list number is the primary substance identifier used by ECHA.

CAS (Chemical Abstract Service) registry number

The CAS number is the substance numerical identifier assigned by the Chemical Abstracts Service, a division of the American Chemical Society, to substances registered in the CAS registry database. A substance identified primarily by an EC or list number may be linked with more than one CAS number, or with CAS numbers that have been deleted. More information about CAS and the CAS registry can be found here.

Molecular formula

The molecular formula identifies each type of element by its chemical symbol and identifies the number of atoms of each element found in one discrete molecule of the substance. This information is only displayed if the substance is well–defined, its identity is not claimed confidential and there is sufficient information available in ECHA’s databases for ECHA’s algorithms to generate a molecular structure.

Molecular structure

The molecular structure is based on structures generated from information available in ECHA’s databases. If generated, an InChI string will also be generated and made available for searching. This information is only displayed if the substance is well-defined, its identity is not claimed confidential and there is sufficient information available in ECHA’s databases for ECHA’s algorithms to generate a molecular structure.

More help available here.

EC / List no.: 200-098-7

CAS no.: 51-43-4

Mol. formula: C9H13NO3

formula
Help Hazard classification and labelling

The ‘Hazard classification and labelling’ section shows the hazards of a substance based on the standardised system of statements and pictograms established under the CLP (Classification Labelling and Packaging) Regulation. The CLP Regulation makes sure that the hazards presented by chemicals are clearly communicated to workers and consumers in the European Union. The CLP Regulation uses the UN Global Harmonised System (GHS) and European Union Specific Hazard Statements (EUH).

This section is based on three sources for information (harmonised classification and labelling (CLH), REACH registrations and CLP notifications). The source of the information is mentioned in the introductory sentence of the hazard statements. When information is available in all sources, the first two are displayed as a priority.

Please note:

The purpose of the information provided under this section is to highlight the substance hazardousness in a readable format. It does not represent a new labelling, classification or hazard statement, neither reflect other factors that affect the susceptibility of the effects described, such as duration of exposure or substance concentration (e.g. in case of consumer and professional uses). Other relevant information includes the following:

  • Substances may have impurities and additives that lead to different classifications. If at least one company has indicated that the substance classification is affected by impurities or additives, this will be indicated by an informative sentence. However, substance notifications in the InfoCard are aggregated independently of the impurities and additives.
  • Hazard statements were adapted to improve readability and may not correspond textually to the hazard statements codes description in the European Union Specific Hazard Statements (EUH) or the UN Global Harmonised System (GHS).

To see the full list of notified classifications and to get more information on impurities and additives relevant to classification please consult the C&L Inventory.

More information about Classification and Labelling is available in the Regulations section of ECHA website.

More help available here.

Harmonised classification and labelling (CLH)

Harmonised classification and labelling is a legally binding classification and labelling for a substance, agreed at European Community level. Harmonisation is based on the substance’s physical, toxicological and eco-toxicological hazard assessment.

The ‘Hazard classification’ and labelling section uses the signal word, pictogram(s) and hazard statements of the substance under the harmonised classification and labelling (CLH) as its primary source of information.

If the substance is covered by more than one CLH entry (e.g. disodium tetraborate EC no. 215–540–4, is covered by three harmonisations: 005–011–00–4; 005–011–01–1 and 005–011–02–9), CLH information cannot be displayed in the InfoCard as the difference between the CLH classifications requires manual interpretation or verification. If a substance is classified under multiple CLH entries, a link to the C&L Inventory is provided to allow users to view CLH information associated with the substance and no text is automatically generated for the InfoCard.

It is possible that a harmonisation is introduced through an amendment to the CLP Regulation. In that case, the ATP (Adaptation to Technical Progress) number is displayed.

More info on CLH can be found here.

Classification and labelling under REACH

If available, additional information on classification and labelling (C&L) is derived from REACH registration dossiers submitted by industry. This information has not been reviewed or verified by ECHA, and may change without prior notice. REACH registration dossiers have greater data requirements (such as supporting studies) than do notifications under CLP.

Notifications under the Classification Labelling and Packaging (CLP) Regulation

If no EU harmonised classification and labelling exists and the substance was not registered under REACH, information derived from classification and labelling (C&L) notifications to ECHA under CLP Regulation is displayed under this section. These notifications can be provided by manufacturers, importers and downstream users. ECHA maintains the C&L Inventory, but does not review or verify the accuracy of the information.

Note that for readability purposes, only the pictograms, signal words and hazard statements referred in more than 5% of the notifications under CLP are displayed.

GHS06: Acute Toxicity

Danger! According to the classification provided by companies to ECHA in CLP notifications this substance is fatal in contact with skin, is toxic if inhaled and is toxic if swallowed.

about INFOCARD - Last updated: 17/12/2019 InfoCard

The InfoCard summarises the non-confidential data of a substance held in the databases of the European Chemicals Agency (ECHA). InfoCards are generated automatically based on the data available at the time of generation.

The quality and correctness of the information submitted to ECHA remains the responsibility of the data submitter. The type of uses and classifications may vary between different submissions to ECHA and for a full understanding it is recommended to consult the source data. Information on applicable regulatory frameworks is also automatically generated and may not be complete or up to date. It is the responsibility of the substance manufacturers and importers to consult official publications, e.g. the electronic edition of the Official Journal of the European Union.

InfoCards are updated when new information is available. The date of the last update corresponds to the publication date of the InfoCard and not necessarily to the date in which the update occurred in the source data.

More help available here.

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Key datasets

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Regulatory context

Here you can find all of the regulations and regulatory lists in which this substance appears, according to the data available to ECHA. This substance has been found in the following regulatory activities (directly, or inheriting the regulatory context of a parent substance):

REACH - Registration, Evaluation, Authorisation and Restriction of Chemicals Regulation
CLP - Classification, Labelling and Packaging
  • A list of substances for which classification and labelling data have been notified to ECHA by manufacturers or importers.
Previous Legislations
  • Substances listed in the EINECS, ELINCS, or NLP inventories.
Help Help

Substance names and other identifiers

Regulatory process names
(-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol
Other
(R)-Adrenaline
Other
(R)-Epinephrine
Other
1,2-Benzenediol, 4-((1R)-1-hydroxy-2-(methylamino)ethyl)-
Other
1,2-Benzenediol, 4-(1-hydroxy-2-(methylamino)ethyl)-, (R)-
Other
1,2-Benzenediol, 4-(1-hydroxy-2-(methylamino)ethyl)-, (theta)-
Other
1-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
Other
1-Adrenalin
Other
1-Epinephrine
Other
4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol
Other
Adnephrine
Other
Adrenaclick
Other
Adrenal
Other
Adrenalin
Other
Adrenalin-Medihaler
Other
Adrenalina
Other
Adrenaline
Other
Adrenalinum
Other
Adrenamine
Other
Adrenapax
Other
Adrenasol
Other
Adrenine
Other
Adrenodis
Other
Adrenohorma
Other
Adrenosan
Other
Adrenutol
Other
Adrin
Other
Antiasthmatique
Other
Asmatane Mist
Other
Asthma meter mist
Other
Asthma-nefrin
Other
Astmahalin
Other
Astminhal
Other
Auvi-Q
Other
Auvi-Q auto-injector
Other
Balmadren
Other
Benzyl alcohol, 3,4-dihydroxy-alpha-((methylamino)methyl)-, (-)-
Other
Bernarenin
Other
Biorenine
Other
Bosmin
Other
Brevirenin
Other
Bronkaid
Other
Bronkaid Mist
Other
Chelafrin
Other
Corisol
Other
Drenamist
Other
Dylephrin
Other
Dyspne-inhal
Other
Epi E Z Pen jr
Other
Epifrin
Other
Epinefrin
Other
Epinefrina
Other
Epinephran
Other
Epinephrine
EC Inventory, Pre-Registration process, Other, EU. Cosmetics Regulation, Annex II, Prohibited Substances
Epinephrinum
Other
Epipen
Other
Epipen E Z Pen
Other
Epipen jr.
Other
Epirenan
Other
Esphygmogenina
Other
Exadrin
Other
Glaucosan
Other
Glycirenan
Other
Haemostasin
Other
Haemostatin
Other
Hektalin
Other
Hemisine
Other
Hemostasin
Other
Hemostatin
Other
Hypernephrin
Other
Hyporenin
Other
Intranefrin
Other
Isoptoepinal
Other
Kidoline
Other
l-Adrenaline
Other
l-Epinephrine
Other
l-Epinephrine (synthetic)
Other
l-Epirenamine
Other
Levoepinephrine
Other
Levorenin
Other
Levorenine
Other
Lyophrin
Other
Methylaminoethanolcatechol
Other
Methylarterenol
Other
Mucidrina
Other
Myosthenine
Other
Mytrate
Other
Nephridine
Other
Nieraline
Other
Paranephrin
Other
Primatene Mist
Other
Renaglandin
Other
Renaleptine
Other
Renalina
Other
Renoform
Other
Renostypticin
Other
Scurenaline
Other
Simplene
Other
Sindrenina
Other
Soladren
Other
Sphygmogenin
Other
Stryptirenal
Other
Styptirenal
Other
Supracapsulin
Other
Supradin
Other
Supranefran
Other
Supranephrane
Other
Supranephrine
Other
Supranol
Other
Suprarenaline
Other
Suprel
Other
Sus-Phrine
Other
Sus-phrine sulfite-free
Other
Symjepi
Other
Sympathin I
Other
Takamina
Other
Takamine
Other
Tokamina
Other
Tonogen
Other
Twinject
Other
Twinject 0.15
Other
Twinject 0.3
Other
Vaponefrin
Other
Vasoconstrictine
Other
Vasodrine
Other
Vasotonin
Other
IUPAC names
(-)-Epinephrin
C&L Inventory
4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
Other
Other identifiers
51-43-4
EC Inventory, C&L Inventory, Pre-Registration process, Other, EU. Cosmetics Regulation, Annex II, Prohibited Substances
CAS number
51028-73-0
Other
CAS number

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