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The new ECHA CHEM database has been released by ECHA. At first this system will contain only substances and data from REACH registration dossiers. For new and updated REACH registration data please check ECHA CHEM. See for more information on the transition to ECHA CHEM. More
Please be aware that REACH registration data here on the current Dissemination Platform is no longer maintained; it remains frozen as of 19th May 2023.
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Registered Substances Factsheets
Substances which have been registered and can be placed on the EEA market by those companies with a valid registration
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Registrant/Supplier | Address | Country | Registration Status | Name | EC / List no. | CAS no. | Last update year | Details |
---|---|---|---|---|---|---|---|---|
Cambrex Profarmaco Milano Srl | via Curiel, 34 20067 Paullo MI Italy | Italy | Active | 1-(3-Chloro-4-hydroxyphenyl)ethanone | 620-213-8 | 2892-29-7 | - | View substance registered dossier |
Selectchemie Italia Srl | Via Messina, 47 20154 Milano Italy | Italy | Active | 1-(3-chlorophenyl)-4-(3-chloropropyl)piperazinium chloride | 258-038-0 | 52605-52-4 | - | View substance registered dossier |
A.C.R.A.F. Spa | Via Amelia 70 00181 Roma Italy | Italy | Active | 1-(3-chlorophenyl)-4-(3-chloropropyl)piperazinium chloride | 258-038-0 | 52605-52-4 | 2016 | View substance registered dossier |
Flavine Europe GmbH | Wehrlestrasse 12 81679 Munich Germany | Germany | Active | 1-(3-chlorophenyl)-4-(3-chloropropyl)piperazinium chloride | 258-038-0 | 52605-52-4 | - | View substance registered dossier |
Fermion Oy | Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland | Finland | Active | 1-(3-chlorophenyl)-4-(3-chloropropyl)piperazinium chloride | 258-038-0 | 52605-52-4 | - | View substance registered dossier |
Chemsafe | Via Ribes 5 10010 Colleretto Giacosa (TO) Italy | Italy | Active | 1-(3-chlorophenyl)-4-(3-chloropropyl)piperazinium chloride | 258-038-0 | 52605-52-4 | - | View substance registered dossier |
Chemosyntha BV | Stedestraat 51 B-8530 Harelbeke West Vlaanderen Belgium | Belgium | Active | 1-(3-chlorophenyl)-4-(3-chloropropyl)piperazinium chloride | 258-038-0 | 52605-52-4 | - | View substance registered dossier |
Trifarma S.p.A. | Via G. Guarini Matteucci 1 20162 Milan (MI) Italy | Italy | Active | 1-(3-chloropropyl)-4-methylpiperazine | 203-181-6 | 104-16-5 | 2018 | View substance registered dossier |
Bayer AG | Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany | Germany | Active | 1-(3-chloropyridin-2-yl)-3-{[5-(trifluoromethyl)-2H-tetrazol-2-yl]methyl}-1H-pyrazole-5-carboxylic acid | 936-882-7 | 1352319-02-8 | 2016; 2017 | View substance registered dossier |
[Confidential] | - | - | - | 1-(3-chloropyridin-2-yl)-3-{[5-(trifluoromethyl)-2H-tetrazol-2-yl]methyl}-1H-pyrazole-5-carboxylic acid | 936-882-7 | 1352319-02-8 | - | View substance registered dossier |
Pliva Hrvatska doo | Prilaz baruna Filipovića 25 10000 Zagreb Croatia | Croatia | Active | 1-(3-ethoxy-4-methoxy-phenyl)-2-(methylthio)ethan-1-one | 944-025-3 | 2093007-28-2 | - | View substance registered dossier |
FINORGA SAS | 497 route de Givors 38670 CHASSE SUR RHONE France | France | Active | 1-(3-iodo-1-isopropyl-1H-pyrazol-4-yl)ethanone | 807-940-8 | 1269440-49-4 | 2021 | View substance registered dossier |
Esteve Quimica, S.A. | Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain | Spain | Active | 1-(3-iodo-1-isopropyl-1H-pyrazol-4-yl)ethanone | 807-940-8 | 1269440-49-4 | - | View substance registered dossier |
BASF SE | Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany | Germany | Active | 1-(3-methoxyphenyl)ethanamine | 700-849-3 | 62409-13-6 | - | View substance registered dossier |
Merck KGaA | Frankfurter Strasse 250 64293 Darmstadt Germany | Germany | Cease Manufacture | 1-(3-Phenyl-cyclohexyl)-propan-1-one | 929-116-8 | - | 2019 | View substance registered dossier |
[Confidential] | - | - | - | 1-(3-tert-butyl-1,3,3-trimethyl-1-alkenyldisiloxanyl)-4-alkylheterocycle | - | - | - | View substance registered dossier |
PROCOS SpA | via Matteotti 249 28062 Cameri Piemonte Italy | Italy | Active | 1-(3-tert-Butyl-5-iodo-4-methoxyphenyl)pyrimidine-2,4(1H,3H)-dione | 800-476-7 | 1132940-53-4 | 2015 | View substance registered dossier |
[Confidential] | - | - | - | 1-(3-tert-Butyl-5-iodo-4-methoxyphenyl)pyrimidine-2,4(1H,3H)-dione | 800-476-7 | 1132940-53-4 | - | View substance registered dossier |
Curia France SAS | ZI de Laville 47240 BON-ENCONTRE France | France | Active | 1-(3-trifluoromethylphenyl)-4-(2-hydroxyethyl)-piperazine, hydrochloride | 611-190-5 | 54711-67-0 | - | View substance registered dossier |
F.I.S. Fabbrica Italiana Sintetici S.p.a. | Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy | Italy | Active | 1-(4,7-dihydro-5H-thieno[2,3-c]pyran-7-yl)- N-methylmethanamine trifluoromethansulfonate | 850-248-6 | 2374784-45-7 | - | View substance registered dossier |
[Confidential] | - | - | - | 1-(4-((2R,5R)-2,5-bis(4-chloro-2-fluoro-5-nitrophenyl)pyrrolidin-1-yl)-2,6-difluorophenyl)-4-(4-fluorophenyl)piperidine | 824-054-7 | 1332356-86-1 | - | View substance registered dossier |
Esteve Quimica, S.A. | Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain | Spain | Active | 1-(4-((4-([1,2,4]triazolo[1,5-a]pyrid-7-yloxy)-3-methylphenyl)amino)quinazolin-6-yl)-3-(1-hydroxy-2-methylpropan-2-yl)thiourea | 856-351-2 | 1429755-58-7 | - | View substance registered dossier |
Merck KGaA | Frankfurter Strasse 250 64293 Darmstadt Germany | Germany | Cease Manufacture | 1-(4-(trans-4-ethylcyclohexyl)phenyl)ethanone | 426-460-6 | 260415-81-4 | 2019 | View substance registered dossier |
Merck KGaA | Frankfurter Strasse 250 64293 Darmstadt Germany | Germany | Cease Manufacture | 1-(4-(trans-4-Propylcyclohexyl)-phenyl)-butan-1-one | 689-242-1 | 95149-34-1 | 2019 | View substance registered dossier |
Merck KGaA | Frankfurter Strasse 250 64293 Darmstadt Germany | Germany | Active | 1-(4-(trans-4-Propylcyclohexyl)-phenyl)-pentan-1-on | 689-247-9 | 95149-35-2 | 2012; 2019 | View substance registered dossier |
Excella GmbH & Co. KG | Nuernberger Str. 12 90537 Feucht Germany | Germany | Active | 1-(4-amino-6,7-dimethoxyquinazolin-2-yl)-4-(2,3-dihydro-1,4-benzodioxine-2-carbonyl)piperazine-1,4-diium acetate methanesulfonate (1/1/1) | 942-972-7 | - | - | View substance registered dossier |
Excella GmbH & Co. KG | Nuernberger Str. 12 90537 Feucht Germany | Germany | Active | 1-(4-amino-6,7-dimethoxyquinazolin-2-yl)-4-(2,3-dihydro-1,4-benzodioxine-2-carbonyl)piperazine-1,4-diium diacetate | 942-971-1 | - | - | View substance registered dossier |
Medichem S.A. | Polígon Industrial de Celrà 17460 Celrà Girona Spain | Spain | Active | 1-(4-AminoPhenyl)-5,6-Dihydro-3-(4-Morpholinyl)-2(1H)-Pyridinone | 884-465-2 | 1267610-26-3 | - | View substance registered dossier |
N.V. Ajinomoto OmniChem S.A. | Cooppallaan 91 9230 Wetteren Oost-Vlaanderen Belgium | Belgium | Active | 1-(4-benzoylpiperazin-1-yl)-2(-7-bromo-4-methoxy-1H-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione | 942-399-2 | 1449413-23-3 | - | View substance registered dossier |
F.I.S. Fabbrica Italiana Sintetici S.p.a. | Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy | Italy | Active | 1-(4-Bromo-2-hydroxyphenyl)-2-(2,5-dibromophenyl)ethanone | 813-148-3 | 1403991-85-4 | - | View substance registered dossier |
Excella GmbH & Co. KG | Nuernberger Str. 12 90537 Feucht Germany | Germany | Active | 1-(4-Chloro-1,1-dimethoxybutyl)-4-fluorobenzene | 696-157-3 | 57390-39-3 | - | View substance registered dossier |
Saltigo GmbH | HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany | Germany | Active | 1-(4-chloro-phenyl)-2-methyl-but-3-en-1-ol | 602-965-9 | 123989-31-1 | 2012 | View substance registered dossier |
Sigma-Aldrich Ireland Ltd | Vale Road . Arklow Co. Wicklow Ireland | Ireland | Active | 1-(4-Chlorophenyl)-1-phenylethanol | 611-881-1 | 59767-24-7 | - | View substance registered dossier |
Saltigo GmbH | HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany | Germany | Active | 1-(4-chlorophenyl)-2-cyclopropyl-propan-1-ol | 619-846-2 | 123989-28-6 | 2011 | View substance registered dossier |
Saltigo GmbH | HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany | Germany | Active | 1-(4-chlorophenyl)-2-cyclopropylpropan-1-one | 602-964-3 | 123989-29-7 | 2012 | View substance registered dossier |
BASF Schwarzheide GmbH | Schipkauer Str. 1 01987 Schwarzheide Brandenburg Germany | Germany | Active | 1-(4-chlorophenyl)pyrazol-3-ol | 616-307-3 | 76205-19-1 | - | View substance registered dossier |
Siegfried St. Vulbas SAS | 530, allée de la Luye 01150 SAINT VULBAS France | France | Cease Manufacture | 1-(4-chlorophenyl)sulfanyl-2-nitrobenzene | 700-088-7 | 6764-10-9 | 2017 | View substance registered dossier |
Lundbeck Pharmaceuticals Italy S.p.A | via quarta strada 2 35129 padova Italy | Italy | Active | 1-(4-fluorophenyl)-4-(4-methylpiperidin-1-yl)butan-1-one | 609-173-2 | 3575-80-2 | - | View substance registered dossier |
OLON Spa | Strada Rivoltana Km 6/7 20053 RODANO Milano Italy | Italy | Active | 1-(4-fluorophenyl)-4-(4-methylpiperidin-1-yl)butan-1-one | 609-173-2 | 3575-80-2 | 2017 | View substance registered dossier |
Archroma Germany GmbH | Kasteler Str. 45 65203 Wiesbaden Germany | Germany | Active | 1-(4-hydrazinophenyl)sulfonyl-2-methyl-propane-2-sulfonic acid | 619-707-6 | 58370-36-8 | - | View substance registered dossier |
Cambrex Karlskoga AB | Bjorkborns Industriomrade 69185 Karlskoga Sweden | Sweden | Active | 1-(4-Hydroxyphenyl)heptane-1,3-dione | 927-036-8 | - | 2018 | View substance registered dossier |
[Confidential] | - | - | - | 1-(4-methoxy-2,3,6-trimethylphenyl)-3-methylpenta-1,4-dien-3-ol | 259-323-2 | 54757-48-1 | - | View substance registered dossier |
OLON Spa | Strada Rivoltana Km 6/7 20053 RODANO Milano Italy | Italy | Cease Manufacture | 1-(4-methoxy-2,3,6-trimethylphenyl)-3-methylpenta-1,4-dien-3-ol | 259-323-2 | 54757-48-1 | 2022 | View substance registered dossier |
Saltigo GmbH | HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany | Germany | Cease Manufacture | 1-(4-methoxyphenyl)-2-[(3-methoxyphenyl)thio] ethanone | 469-300-0 | 63675-73-0 | 2018 | View substance registered dossier |
Eli Lilly Kinsale Limited | Dunderrow Kinsale P17 NY71 Cork Co. Cork Ireland | Ireland | Active | 1-(4-methoxyphenyl)-2-[(3-methoxyphenyl)thio] ethanone | 469-300-0 | 63675-73-0 | 2010; 2012; 2017 | View substance registered dossier |
MINAKEM Beuvry Production SAS | 145, Chemin des Lilas 59310 Beuvry-la-Forêt France | France | Cease Manufacture | 1-(4-methoxyphenyl)-N-methylmethanamine | 662-855-1 | 702-24-9 | 2019 | View substance registered dossier |
BASF SE | Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany | Germany | Active | 1-(4-Methoxyphenyl)ethanamine | 700-847-2 | 6298-96-0 | - | View substance registered dossier |
Saltigo GmbH | HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany | Germany | Active | 1-(4-methylphenyl)ethylamine | 443-160-0 | 586-70-9 | 2011; 2014; 2017; 2018 | View substance registered dossier |
Arran Chemical Company Ltd | Monksland Industrial Estate N37DN24 Athlone Co. Roscommon Ireland | Ireland | Active | 1-(4-methylphenyl)ethylamine | 443-160-0 | 586-70-9 | - | View substance registered dossier |
DKSH Great Britain Ltd. | 32 Threadneedle Street EC2R 8AY London United Kingdom | United Kingdom | No longer Valid | 1-(4-methylphenyl)ethylamine | 443-160-0 | 586-70-9 | 2021 | View substance registered dossier |
RANKE QUIMICA S.A. | Ctra. Nacional II, Km 593 08740 Sant Andreu de la Barca Barcelona Spain | Spain | Active | 1-(4-tert-butylphenyl)-4-(4-hydroxypiperidin-1-yl)butan-1-one | 619-298-4 | 97928-18-2 | - | View substance registered dossier |
Lundbeck Pharmaceuticals Italy S.p.A | via quarta strada 2 35129 padova Italy | Italy | Active | 1-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)ethanone | 840-270-4 | 13080-75-6 | - | View substance registered dossier |
Aceto France SAS | 3 Rue de Genève CS 50363 BP 50367 Lyon Cedex 06 France | France | Active | 1-(5-bromo-2-fluorophenyl)ethanone | 806-758-6 | 198477-89-3 | - | View substance registered dossier |
FINORGA SAS | 497 route de Givors 38670 CHASSE SUR RHONE France | France | Active | 1-(5-Bromo-2-methoxyphenyl)adamantane | 689-408-3 | 104224-63-7 | - | View substance registered dossier |
PCAS | 21 Chemin de la Sauvegarde 21 Ecully Parc - CS33167 69134 ECULLY France | France | Active | 1-(5-chloro-2-thienyl)ethan-1-one | 228-630-3 | 6310-09-4 | - | View substance registered dossier |
MinAscent Leuna Production GmbH | Am Haupttor Gebäude 4208 06237 Leuna Germany | Germany | Active | 1-(5-methyl-2-furyl)propan-1-one | 234-215-8 | 10599-69-6 | - | View substance registered dossier |
F.I.S. Fabbrica Italiana Sintetici S.p.a. | Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy | Italy | Active | 1-(6-Methylpyridin-3-yl)-2-[4-(methylsulfonyl)phenyl]ethanone | 606-942-4 | 221615-75-4 | - | View substance registered dossier |
Esteve Quimica, S.A. | Torre Esteve Passeig de la Zona Franca, 109, 4ª Planta 08038 Barcelona Barcelona Spain | Spain | Cease Manufacture | 1-(7-bromo-9,9-difluoro-9H-fluoren-2-yl)-2-chloroethanone | 696-512-2 | 1378387-81-5 | 2021 | View substance registered dossier |
ERREGIERRE SPA | Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy | Italy | Active | 1-(acetyl)thiosemicarbazide | 218-956-4 | 2302-88-7 | - | View substance registered dossier |
LA MESTA CHIMIE FINE | 1336 Route de l'Estéron 06830 GILETTE France | France | Active | 1-(allyl)pyrrolidine-2-methylamine | 247-467-9 | 26116-13-2 | - | View substance registered dossier |
Fine Organics Limited | Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom | United Kingdom | No longer Valid | 1-(allyloxy)-2-methyl-1-oxopropan-2-yl 2-chloro-5-nitrobenzoate | 696-317-2 | 174489-76-0 | 2021 | View substance registered dossier |
F.I.S. Fabbrica Italiana Sintetici S.p.a. | Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy | Italy | Active | 1-(aminomethyl)cyclohexaneacetic acid hydrochloride | 262-075-8 | 60142-95-2 | - | View substance registered dossier |
Sicor - Società Italiana Corticosteroidi S.r.l. | Piazzale Luigi Cadorna 4 20123 Milano (MI) Italy | Italy | Active | 1-(aminomethyl)cyclohexaneacetic acid hydrochloride | 262-075-8 | 60142-95-2 | - | View substance registered dossier |
ERREGIERRE SPA | Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy | Italy | Active | 1-(aminomethyl)cyclohexaneacetic acid hydrochloride | 262-075-8 | 60142-95-2 | - | View substance registered dossier |
LA MESTA CHIMIE FINE | 1336 Route de l'Estéron 06830 GILETTE France | France | Active | 1-(benzhydrylamino)ethyl-hydroxy-oxophosphanium | 692-012-3 | 65577-30-2 | - | View substance registered dossier |
OLON Spa | Strada Rivoltana Km 6/7 20053 RODANO Milano Italy | Italy | Active | 1-(benzyloxy)-4-[2-(cyclopropylmethoxy)ethyl]benzene | 613-308-0 | 63659-15-4 | 2017 | View substance registered dossier |
FINORGA - MOURENX | avenue du lac 64150 MOURENX France | France | Active | 1-(benzyloxy)-4-[2-(cyclopropylmethoxy)ethyl]benzene | 613-308-0 | 63659-15-4 | - | View substance registered dossier |
Patheon Austria GmbH & Co KG | St. Peterstrasse 25 A-4020 Linz Austria | Austria | Active | 1-(bromomethyl)-3,5-bis(trifluoromethyl)benzene | 250-971-1 | 32247-96-4 | - | View substance registered dossier |
REACh ChemConsult GmbH | Strehlener Str. 14 01069 Dresden Germany | Germany | Active | 1-(chloromethyl)naphthalene | 201-678-2 | 86-52-2 | 2018 | View substance registered dossier |
ChampionX Europe B.V. | Oude Rhijnhofweg 17 NL-2342BB Oegstgeest Oegstgeest Netherlands | Netherlands | Active | 1-(chloromethyl)naphthalene | 201-678-2 | 86-52-2 | 2021 | View substance registered dossier |
Merck Santé s.a.s. | 37, rue Saint Romain TSA 40123 69379 LYON CEDEX France | France | Cease Manufacture | 1-(chloromethyl)naphthalene | 201-678-2 | 86-52-2 | 2022 | View substance registered dossier |
PROCOS SpA | via Matteotti 249 28062 Cameri Piemonte Italy | Italy | Active | 1-(chlorophenylmethyl)-2-methylbenzene | 431-450-1 | 41870-52-4 | 2022 | View substance registered dossier |
LAXMI ORGANIC INDUSTRIES (EUROPE) B.V. | BURGEMEESTER FEITHPLEIN 11 2273 BZ VOORBURG Netherlands | Netherlands | Cease Manufacture | 1-(dichloromethyl)-2-(trichloromethyl)benzene | 220-371-4 | 2741-57-3 | 2019 | View substance registered dossier |
LAXMI ORGANIC INDUSTRIES (EUROPE) B.V. | BURGEMEESTER FEITHPLEIN 11 2273 BZ VOORBURG Netherlands | Netherlands | Cease Manufacture | 1-(dichloromethyl)-2-(trifluoromethyl)benzene | 615-161-8 | 707-72-2 | 2019 | View substance registered dossier |
FRESENIUS KABI iPSUM s.r.l. | Via Roma, 108 20060 Cassina de' Pecchi (MI) Italy | Italy | Active | 1-(dimethoxymethyl)hexahydro-1H-azepine | 251-282-9 | 32895-16-2 | - | View substance registered dossier |
MINAKEM Beuvry Production SAS | 145, Chemin des Lilas 59310 Beuvry-la-Forêt France | France | Active | 1-(diphenylmethyl)azetidin-3-amine acetate (1:1) | 876-093-4 | 928672-57-5 | - | View substance registered dossier |
MINAKEM Beuvry Production SAS | 145, Chemin des Lilas 59310 Beuvry-la-Forêt France | France | Active | 1-(diphenylmethyl)azetidin-3-ol | 606-074-6 | 18621-17-5 | - | View substance registered dossier |
MINAKEM Beuvry Production SAS | 145, Chemin des Lilas 59310 Beuvry-la-Forêt France | France | Active | 1-(diphenylmethyl)azetidin-3-yl methanesulfonate | 608-857-8 | 33301-41-6 | - | View substance registered dossier |
Curia France SAS | ZI de Laville 47240 BON-ENCONTRE France | France | Active | 1-(ethoxyethyl)-4-bromo-1H-pyrazole | 692-014-4 | 1024120-52-2 | - | View substance registered dossier |
PALCHEM | Rue du Transvaal BP22 62143 ANGRES France | France | Active | 1-(ethoxymethoxy)-4-methyl-benzene | 609-065-5 | 35117-05-6 | - | View substance registered dossier |
Nouryon Functional Chemicals B.V. | Haaksbergweg 88 1101 BZ Amsterdam The Netherlands Netherlands | Netherlands | Active | 1-(ethoxymethoxy)-4-methyl-benzene | 609-065-5 | 35117-05-6 | 2019 | View substance registered dossier |
A.C.R.A.F. Spa | Via Amelia 70 00181 Roma Italy | Italy | Active | 1-(m-chlorophenyl)piperazine | 229-654-7 | 6640-24-0 | - | View substance registered dossier |
Chemsafe | Via Ribes 5 10010 Colleretto Giacosa (TO) Italy | Italy | Active | 1-(m-chlorophenyl)piperazine | 229-654-7 | 6640-24-0 | - | View substance registered dossier |
Chemosyntha BV | Stedestraat 51 B-8530 Harelbeke West Vlaanderen Belgium | Belgium | Active | 1-(m-chlorophenyl)piperazine | 229-654-7 | 6640-24-0 | - | View substance registered dossier |
Inchem GmbH | Bahnhofstr. 2a D-51379 Leverkusen Germany | Germany | Active | 1-(N,N-bis(2-hydroxyethyl)amino)propan-2-ol | 229-764-5 | 6712-98-7 | 2020 | View substance registered dossier |
F.I.S. Fabbrica Italiana Sintetici S.p.a. | Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy | Italy | Active | 1-(o-chlorobenzyl)-1H-pyrrole | 245-830-6 | 23694-46-4 | - | View substance registered dossier |
BASF SE | Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany | Germany | Cease Manufacture | 1-(p-tolyl)ethanamine | 937-697-4 | - | 2020 | View substance registered dossier |
sanofi chimie | 82 avenue Raspail 94250 Gentilly France | France | Active | 1-(pyrimidin-2-yl)methanamine hydrochloride (1:1) | 692-058-4 | 372118-67-7 | - | View substance registered dossier |
Fermion Oy | Koivu-Mankkaan tie 6 A FI-02101 Espoo Finland | Finland | Active | 1-(tetrahydro-2H-pyran-2-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole | 640-188-7 | 903550-26-5 | - | View substance registered dossier |
Curia France SAS | ZI de Laville 47240 BON-ENCONTRE France | France | Active | 1-(tetrahydro-2H-pyran-2-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole | 640-188-7 | 903550-26-5 | - | View substance registered dossier |
OLON Spa | Strada Rivoltana Km 6/7 20053 RODANO Milano Italy | Italy | Active | 1-(tetrahydro-2H-pyran-2-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole | 640-188-7 | 903550-26-5 | 2017 | View substance registered dossier |
Curia Italy S.r.l. | VIA DEL VECCHIO POLITECNICO, n. 9 20121 Milano Italy | Italy | Active | 1-(tetrahydro-2H-pyran-2-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole | 640-188-7 | 903550-26-5 | - | View substance registered dossier |
Chemische Fabrik Karl Bucher GmbH | An der Guenz 1 89367 Waldstetten Germany | Germany | Active | 1-(trimethylsilyloxy)-hexane | 823-658-8 | 17888-62-9 | 2018; 2022 | View substance registered dossier |
Symrise AG | Mühlenfeldstraße 1 37603 Holzminden Germany | Germany | Active | 1-(vinyloxy)propane | 212-123-9 | 764-47-6 | 2020 | View substance registered dossier |
CellMark Deutschland GmbH | Parsevalstraße 9A D - 40468 Düsseldorf Germany Germany | Germany | Active | 1-(vinyloxy)propane | 212-123-9 | 764-47-6 | - | View substance registered dossier |
Fine Organics Limited | Seal Sands TS2 1UB Middlesbrough Teesside United Kingdom | United Kingdom | No longer Valid | 1-({[(2,5-dioxopyrrolidin-1-yl)oxy]carbonyl}oxy)ethyl 2-methylpropanoate | 700-402-2 | 860035-10-5 | 2021 | View substance registered dossier |
Thermofisher Scientific Cork Ltd. | Currabinny P43 AY66 Carrigaline Co. Cork Ireland | Ireland | Cease Manufacture | 1-({[(2,5-dioxopyrrolidin-1-yl)oxy]carbonyl}oxy)ethyl 2-methylpropanoate | 700-402-2 | 860035-10-5 | 2021 | View substance registered dossier |
ERREGIERRE SPA | Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy | Italy | Active | 1-(β-phenethyl)-4-piperidone | 254-613-5 | 39742-60-4 | - | View substance registered dossier |
FERRANIA CHEMICALS S.R.L. | Viale della Libertà, 57 17014 Cairo Montenotte (SV) Italy | Italy | Cease Manufacture | 1-(β-phenethyl)-4-piperidone | 254-613-5 | 39742-60-4 | 2019 | View substance registered dossier |
INTEROR | 49, rue d'Ostende F-62100 CALAIS France | France | Active | 1-(β-phenethyl)-4-piperidone | 254-613-5 | 39742-60-4 | - | View substance registered dossier |
Arevipharma GmbH | Meißner Straße 35 01445 Radebeul Saxony Germany | Germany | Active | 1-(β-phenethyl)-4-piperidone | 254-613-5 | 39742-60-4 | - | View substance registered dossier |
IFF Benicarlo, S.L. | Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain | Spain | Active | 1-[(1R,2S)-2,6,6-trimethylcyclohex-3-en-1-yl]ethanone | 800-278-0 | 41435-93-2 | - | View substance registered dossier |
[Confidential] | - | - | - | 1-[(1R,2S)-2,6,6-trimethylcyclohex-3-en-1-yl]ethanone | 800-278-0 | 41435-93-2 | - | View substance registered dossier |
Novartis Ringaskiddy Limited | . . Ringaskiddy County Cork Ireland | Ireland | Active | 1-[(1Ξ,2Ξ)-2-Chloro-1-hydroxy-3-(quinolin-6-yl)propyl]pyrrolidine-2,5-dione | 811-462-5 | 1197377-31-3 | 2023 | View substance registered dossier |
F.I.S. Fabbrica Italiana Sintetici S.p.a. | Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy | Italy | Active | 1-[(1Ξ,2Ξ)-2-Chloro-1-hydroxy-3-(quinolin-6-yl)propyl]pyrrolidine-2,5-dione | 811-462-5 | 1197377-31-3 | - | View substance registered dossier |
Excella GmbH & Co. KG | Nuernberger Str. 12 90537 Feucht Germany | Germany | Active | 1-[(2,6-difluorophenyl)methyl]-5-[(dimethylamino)methyl]-3-(6-methoxypyridazin-3-yl)-6-(4-nitrophenyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione—hydrogen chloride (1/1) | 858-184-0 | 1589503-99-0 | 2021 | View substance registered dossier |
Fareva La Vallée | 928 avenue Lavoisier ZI de Blavozy 43700 Saint Germain Laprade Auvergne France | France | Active | 1-[(2,6-difluorophenyl)methyl]-5-[(dimethylamino)methyl]-3-(6-methoxypyridazin-3-yl)-6-(4-nitrophenyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione—hydrogen chloride (1/1) | 858-184-0 | 1589503-99-0 | - | View substance registered dossier |
Gedeon Richter Plc. | Gyomroi ut 19-21 1103 Budapest Hungary | Hungary | Active | 1-[(2,6-difluorophenyl)methyl]-5-[(dimethylamino)methyl]-3-(6-methoxypyridazin-3-yl)-6-(4-nitrophenyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione—hydrogen chloride (1/1) | 858-184-0 | 1589503-99-0 | - | View substance registered dossier |
ERREGIERRE SPA | Via Francesco Baracca, 19 24060 SAN PAOLO D'ARGON BERGAMO Italy | Italy | Active | 1-[(2-Chlorophenyl)(diphenyl)methyl]-1H-imidazole nitrate | 807-571-2 | 37594-64-2 | - | View substance registered dossier |
OLON Spa | Strada Rivoltana Km 6/7 20053 RODANO Milano Italy | Italy | Active | 1-[(2-Chlorophenyl)(diphenyl)methyl]-1H-imidazole nitrate | 807-571-2 | 37594-64-2 | 2016; 2022 | View substance registered dossier |
Bayer AG | Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany | Germany | Active | 1-[(2-fluorophenyl)methyl]pyrazolo[3,4-b]pyridine-3-carbonitrile | 849-893-6 | 256376-65-5 | - | View substance registered dossier |
Synthesia, a.s. | Semtín103 53002 Pardubice Czech Republic | Czech Republic | Active | 1-[(2-hydroxy-4-nitrophenyl)azo]-2-naphthol | 229-214-4 | 6434-57-7 | - | View substance registered dossier |
Flamma S.p.a. | via Bedeschi, 22 24040 Chignolo d'Isola Bergamo Italy | Italy | Active | 1-[(2-isopropyl-1,3-thiazol-4-yl)methyl]-1-methyl-3-[(3S)-2-oxotetrahydrofuran-3-yl]urea | 700-850-9 | - | - | View substance registered dossier |
Saltigo GmbH | HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany | Germany | Cease Manufacture | 1-[(2-Propenylthio)carbonyl]-4-(2-methylphenyl)-5-amino-1H-pyrazol-3-one | 700-691-5 | 473799-16-5 | 2020 | View substance registered dossier |
IFF Benicarlo, S.L. | Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain | Spain | Active | 1-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]pyrrolidine-2,5-dione | 700-068-8 | 103953-71-5 | - | View substance registered dossier |
Reuter Chemische Apparatebau e.K. | Engesserstrasse 4b 79108 Freiburg Germany | Germany | Active | 1-[(2R)-6-Fluoro-3,4-dihydro-2H-chromen-2-yl]ethanone | 700-612-4 | - | - | View substance registered dossier |
F.I.S. Fabbrica Italiana Sintetici S.p.a. | Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy | Italy | Active | 1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl]pyrimidine-2,4(1H,3H)-dione | 810-481-6 | 863329-66-2 | - | View substance registered dossier |
EUROAPI Germany GmbH | Brüningstraße 50 65926 Frankfurt am Main Germany | Germany | Active | 1-[(2R,6S)-6-(Hydroxymethyl)-4-(triphenylmethyl)-2-morpholinyl]-5-methyl-2,4(1H,3H)-pyrimidinedione | 854-917-3 | 914361-76-5 | - | View substance registered dossier |
MinAscent Leuna Production GmbH | Am Haupttor Gebäude 4208 06237 Leuna Germany | Germany | Active | 1-[(2S)-2-(benzyloxy)propanoyl]pyrrolidine | 601-832-2 | 122151-32-0 | - | View substance registered dossier |
Reuter Chemische Apparatebau e.K. | Engesserstrasse 4b 79108 Freiburg Germany | Germany | Active | 1-[(2S)-6-Fluoro-3,4-dihydro-2H-chromen-2-yl]ethanone | 700-605-6 | - | - | View substance registered dossier |
MINAKEM Beuvry Production SAS | 145, Chemin des Lilas 59310 Beuvry-la-Forêt France | France | Active | 1-[(2S,3S)-2-(benzyloxy)pentan-3-yl]-N-{4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl}hydrazine-1-carboxamide | 447-870-1 | - | 2019; 2021 | View substance registered dossier |
[Confidential] | - | - | - | 1-[(2S,3S)-2-(benzyloxy)pentan-3-yl]-N-{4-[4-(4-hydroxyphenyl)piperazin-1-yl]phenyl}hydrazine-1-carboxamide | 447-870-1 | - | - | View substance registered dossier |
RECORDATI SPA | Via Mediana Cisterna, 4 04011 Campoverde di Aprilia lazio Italy | Italy | Active | 1-[(3,3-diphenylpropyl)(methyl)amino]-2-methyl-2-propanol | 700-254-9 | 100442-33-9 | 2010; 2015 | View substance registered dossier |
RECORDATI SPA | Via Mediana Cisterna, 4 04011 Campoverde di Aprilia lazio Italy | Italy | Active | 1-[(3,4-dimethoxyphenyl)methyl]-3,4-dihydro-6,7-dimethoxyisoquinoline | 230-148-3 | 6957-27-3 | - | View substance registered dossier |
Indivior UK Ltd | Henry Boot Way HU4 7DY Hull United Kingdom | United Kingdom | No longer Valid | 1-[(5α,7α)-4,5-epoxy-18,19-dihydro-3,6-dimethoxy-17-methyl-6,14-ethenomorphinan-7-yl]ethanone | 240-326-2 | 16196-82-0 | 2021 | View substance registered dossier |
Siegfried PharmaChemikalien Minden GmbH | Karlstr. 15-39, 42-44 32423 Minden Nordrhein-Westphalen Germany | Germany | Active | 1-[(5α,7α)-4,5-epoxy-18,19-dihydro-3,6-dimethoxy-17-methyl-6,14-ethenomorphinan-7-yl]ethanone | 240-326-2 | 16196-82-0 | - | View substance registered dossier |
Macfarlan Smith Limited | Wheatfield Road EH11 2QA Edinburgh United Kingdom | United Kingdom | No longer Valid | 1-[(5α,7α)-4,5-epoxy-18,19-dihydro-3,6-dimethoxy-17-methyl-6,14-ethenomorphinan-7-yl]ethanone | 240-326-2 | 16196-82-0 | 2021 | View substance registered dossier |
Alkaloida Chemical Company Zrt. | Kabay Janos 29 H-4440 Tiszavasvari Hungary | Hungary | Active | 1-[(5α,7α)-4,5-epoxy-18,19-dihydro-3,6-dimethoxy-17-methyl-6,14-ethenomorphinan-7-yl]ethanone | 240-326-2 | 16196-82-0 | 2018 | View substance registered dossier |
Macfarlan Smith Limited | Wheatfield Road EH11 2QA Edinburgh United Kingdom | United Kingdom | No longer Valid | 1-[(5α,7α)-4,5-epoxy-3,6-dimethoxy-17-methyl-6,14-ethenomorphinan-7-yl]ethanone | 239-393-0 | 15358-22-2 | 2021 | View substance registered dossier |
Alkaloida Chemical Company Zrt. | Kabay Janos 29 H-4440 Tiszavasvari Hungary | Hungary | Active | 1-[(5α,7α)-4,5-epoxy-3,6-dimethoxy-17-methyl-6,14-ethenomorphinan-7-yl]ethanone | 239-393-0 | 15358-22-2 | 2018 | View substance registered dossier |
Indivior UK Ltd | Henry Boot Way HU4 7DY Hull United Kingdom | United Kingdom | No longer Valid | 1-[(5α,7α)-4,5-epoxy-3,6-dimethoxy-17-methyl-6,14-ethenomorphinan-7-yl]ethanone | 239-393-0 | 15358-22-2 | 2021 | View substance registered dossier |
F.I.S. Fabbrica Italiana Sintetici S.p.a. | Viale Milano, 26 36075 Montecchio Maggiore (VI) Veneto Italy | Italy | Active | 1-[(7S)-4,7-dihydro-5H-thieno[2,3-c]pyran-7-yl]-N-methylmethanamine (2R) | 850-249-1 | 2374784-46-8 | - | View substance registered dossier |
[Confidential] | - | - | - | 1-[(benzyloxy)carbonyl]-4-ethyl-2,5-dihydro-1H-pyrrole-3-carboxylic acid | 813-192-3 | 1869118-25-1 | - | View substance registered dossier |
Saltigo GmbH | HSEQ-RA Kaiser-Wilhelm-Allee 40 51373 Leverkusen Germany | Germany | Active | 1-[(difluoromethyl)sulfonyl]-3-(4,6-dimethoxy-1,3,5-triazin-2-yl)-7-fluoro-1H-indol-2-ol | 930-430-2 | 1383692-20-3 | - | View substance registered dossier |
Bayer AG | Kaiser-Wilhelm-Allee 1 51373 Leverkusen Germany | Germany | Active | 1-[(difluoromethyl)sulfonyl]-3-(4,6-dimethoxy-1,3,5-triazin-2-yl)-7-fluoro-1H-indol-2-ol | 930-430-2 | 1383692-20-3 | 2016 | View substance registered dossier |
MINAKEM Beuvry Production SAS | 145, Chemin des Lilas 59310 Beuvry-la-Forêt France | France | Cease Manufacture | 1-[(diphenylmethylidene)amino]cyclopropanecarbonitrile | 811-596-4 | 89985-88-6 | 2019 | View substance registered dossier |
Siegfried St. Vulbas SAS | 530, allée de la Luye 01150 SAINT VULBAS France | France | Active | 1-[(tert-butoxy)carbonyl]piperidine-4-carboxylic acid | 700-076-1 | 84358-13-4 | - | View substance registered dossier |
IFF Benicarlo, S.L. | Avda. Felipe Klein 2 12580 Benicarlo Castellon Spain | Spain | Active | 1-[1,6-dimethyl-3-(4-methylpent-3-enyl)-3-cyclohexen-1-yl]ethan-1-one | 259-173-8 | 54464-54-9 | - | View substance registered dossier |
Symrise Granada, S.A.U. | Crta. Armilla Km 2, 5 18100 Armilla Granada Spain | Spain | Active | 1-[1,6-dimethyl-4-(4-methylpent-3-enyl)-3-cyclohexen-1-yl]ethan-1-one | 260-772-1 | 57499-57-7 | - | View substance registered dossier |
Symrise AG | Mühlenfeldstraße 1 37603 Holzminden Germany | Germany | Active | 1-[1,6-dimethyl-4-(4-methylpent-3-enyl)-3-cyclohexen-1-yl]ethan-1-one | 260-772-1 | 57499-57-7 | - | View substance registered dossier |
I dati provengono dai fascicoli di registrazione presentati all'ECHA entro la data indicata come ultimo aggiornamento. La fascia totale di tonnellaggio è compilata a partire da tutti i fascicoli, con due eccezioni; ogni fascia di tonnellaggio per la quale è stata avanzata una richiesta di riservatezza e ogni quantità utilizzata come sostanza intermediaria per produrre una sostanza chimica diversa. La fascia totale di tonnellaggio pubblicata non corrisponde necessariamente alla fascia o alle fasce di tonnellaggio registrate.
Si prega di notare che alcune informazioni sulle sostanze registrate possono appartenere a terzi. L'uso di tali informazioni può pertanto essere soggetto alla previa autorizzazione da parte di proprietari terzi. Per maggiori informazioni si prega di consultare l'avviso legale.
Si prega di notare che le informazioni sulle proprietà chimiche delle sostanze registrate sono accessibili direttamente tramite eChemPortal.
RELATED INFORMATION
- Registered substances information
- How to determine what will be published (Data Submission Manual 15)
- Understanding REACH Regulation
- Q&A on registered substances
- What is an Infocard? [PDF]
- What is a Registered substance Factsheet? [PDF]
- eChemPortal
- REACH study results download
- REACH Regulation
- ECHA Legal notice
Welcome to the REACH Registered Substance Factsheets
Here you will find details from REACH registrations submitted to ECHA. Registrations under REACH can be submitted either jointly – where a group of legal entities pool their data – or individually. The set of details from each published joint or individual submission is presented as a row in the results table. For each row there is also an ‘eye’ icon leading to the detailed factsheet which contains the entire public dataset, following the IUCLID format.
Note that there can be more than one joint or individual submission for the same substance, thus there can be cases where one substance is covered by many REACH registered substance factsheets.
Note too, that as mentioned in the Legal Notice of the ECHA website, ECHA does not give any guarantees or warranties regarding the quality and correctness of the published information. The information in the portal is published ‘as provided’ by industry, and its accuracy has not been verified by ECHA. ECHA is also not in a position to intervene with, edit or correct the published data; this can only be done by the registrant responsible for its submission.
Finally, please note that the information may be protected and its use may require prior permission from its owner (see the ECHA website Legal Notice more details).
All substances table
The “All substances” table gives an overview of all the REACH registered substance factsheets on file at ECHA. Since this covers all data ever submitted since the entry into force of the REACH Regulation, there are some substances which are no longer considered registered under REACH in the EU / EEA. These can be for example substances that were registered only in the UK; since Brexit they are no longer registered in the EU / EEA.
The following columns are presented in the “All substances” table:
- Public substance identity – the best available non-confidential substance name, EC, and CAS numbers.
- Registration status – indicating the calculated registration status for the whole factsheet: Active – is being manufactured or imported to the EEA by one or more registrants; Cease Manufacture - is no longer being manufactured or imported above 1 tone per calendar year. All registrants of the substance have reported a cease of manufacture or import; or No longer valid - no longer considered registered under REACH and not currently allowed to be manufactured or imported to the EEA, until the substance is registered again.
- Registration type – indicating whether a given factsheet contains data from a REACH full registration, REACH intermediate registration, or only a limited set of data inherited from a NONS notification.
- Submission type – indicating whether the data in a given factsheet was submitted jointly or individually.
- Total tonnage band – calculated per factsheet from all contributing registrations, based on the estimated quantity of the substance placed on the market. Data is excluded from dossiers where the tonnage is claimed confidential, from Intermediate registration dossiers, and from NONs which have not been updated.
- Last updated – indicating the date on which this registered substance factsheet was last modified with new or updated data, based on an industry submission.
- ‘Eye’ icon linking to the full factsheet.
Searching
The search for REACH registered substance factsheets is divided into logically separated blocks of related search filters. Note that the search works so that if you provide filters in different blocks, then the results returned must match the filters in block 1 AND those in block 2 etc. Searches are conducted on all the public data included in all published REACH registrations.
Substance identity
In this block you can search by substance identifiers, under filters for Name, EC / List number, and CAS number. Full or partial identifiers can be used. And under the Name filter you can search by any substance name of any kind from any source. Other numerical identifiers such as Harmonised C&L Index number, or PIC CN code can also optionally be used.
Administrative data
In this block you can search by administrative information relating to REACH registered substance factsheets:
- Registration type – picklist of Full, Intermediate, NONS
- Registration status – picklist of Active, Cease Manufacture, No longer valid
- Submission type – Individual or Joint
- Country in which registered – picklist of current and former EU / EEA member states from which REACH registrations were received
- First published date – the date when a REACH registration factsheet was first published
- Last update date – the last date when any registrant / supplier submission contributing to a given REACH registration factsheet was submitted
- Last update year – the year in which any registrant / supplier last made an update submission included in a given REACH registration factsheet
- Registrant / supplier name – where available and not claimed confidential
- Registration number – where available and not claimed confidential
- Registrant address – where available and not claimed confidential
Substance data
In this block you can search by substance related data from REACH registered substance factsheets:
- Tonnage band – picklist of Tonnage range, Tonnage Confidential, Intermediate use only
- Selected total tonnage band range – available only if Tonnage range is selected, and allows to filter REACH registered substance factsheets within any selected min and max value
- Substance has nanoform – picklist of Yes, No
- PBT assessment outcome – picklist of all possible PBT assessment outcomes
- CSA performed – picklist of Yes, No
Use and exposure
In this block you can search by elements relating to how use and exposure are encoded in REACH registrations.
Under the Life cycle option you can select one or more life cycle stages. The search results returned will include only factsheets containing uses reported under the selected life cycle stages.
Under the Category option there are modal popups for each of the use descriptor categories – Product, Sector of use, Process, Environmental release, and Article categories. In each of these are multi select picklists for all the related descriptor codes. The search results returned will include only factsheets containing uses which include the selected descriptor codes.
Note that the Life cycle and Category options work together, so that if a life cycle stage and Category options are both selected the search results will include factsheets containing specific uses in the selected life cycle stage, and where the use includes the selected descriptor codes.
With the search operator option you can select to refine how the search works. AND refines results and returns only those factsheets where ALL the search filter criteria are met. OR broadens the results and returns factsheets where ANY of the selected search filter criteria are met.
The factsheets
There is always a detailed factsheet per joint or individual submission, and it is generated based primarily on the IUCLID format.
The factsheet header begins with the identity of the substance in question, to which the factsheet is linked. The substance identity should always be aligned with that shown in the related substance Infocard. Note that since the Infocard refreshes daily, whereas the factsheet sometimes refreshes on a slower pace, sometimes the data may be out of alignment. In such cases it will always realign as quickly as possible.
The substance identification is enriched with the data provided in the relevant IUCLID section of the primary submitted dossier – either the joint submission lead, or the single individual submission.
In this section are also provided the type of substance, all other identifiers such as trade names, common names, other names etc, as well as all distinct submitted compositions for the substance.
Next is a page covering administrative type information from the data submitted, including:
Registration details, on the total tonnage band informed to ECHA, the registration type, first published and last updated dates, and whether a chemical safety assessment has been performed.
Registrant / supplier details, giving the identity and status of registrants / suppliers, except where the identity has been claimed confidential.
Registration numbers, giving again the identity and status of registration numbers, except where claimed confidential.
Contact persons responsible for the SDS, giving the non-confidential SDS contacts provided to ECHA.
The remainder of the factsheet faithfully follows the IUCLID structure, covering the C&L and PBT, Manufacture, use, and exposure, Physical and chemical properties, Environmental fate and pathways, Ecotoxicological information, Toxicological information, Analytical methods (if available), Guidance on safe use, Assessment reports, and Reference substances.