Registration Dossier
Registration Dossier
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EC number: 700-678-4 | CAS number: 1076-12-6
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 27 September 2011 - 12 June 2013
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: The study was performed according to OECD test guidelines and in compliance with GLP.
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- 6
- Temp.:
- 25 °C
- Remarks on result:
- other: The result is a Lg Pow value and as such has no units
- Conclusions:
- The Partition Coefficient (log10Pow value) of TCD was determined to be 6.0 at 25 °C.
Reference
Description of key information
TCD was found to have a log10Pow value of 6.0.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 6
- at the temperature of:
- 25 °C
Additional information
A partition coefficient determination was conducted as part of a package of physico-chemical testing for TCD (Huntingdon Life Sciences, 2013, Study number VHJ0054). The testing was conducted in compliance with GLP, and the partition coefficient determination was performed according to OECD test guideline 117 and EC test method A.8.
TCD was found to have a log10Pow value of 6.0.
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