EU-MEDICAL_DEVICES_REGULATION-ANX_I_SEC_10

Medical Devices Regulation - Hazardous Substances

EU. Hazardous Substances for Purposes of Medical Devices Regulation 2017/745/EU, 5 May 2017, as amended by Regulation 2020/561/EU, 24 April 2020

This list contains hazardous substances for purposes of the Medical Devices Regulation (MDR), based on the legislation's Annex I general safety and performance requirements, including for chemical, physical and biological properties. Specifically, the non-exhaustive database is derived from: Table 3 of Annex VI to CLP, REACH Candidate List of SVHCs, and Directive 2000/54/EC's Annex III (Biological Agents list).

Last updated 28 juni 2024. Database contains 4917 unique substances/entries.

Filter the list

Viser 1 - 50 af 4.917 resultater.

Substance Name	EC No.	CAS No.	EU CLP (1272/2008)	EU REACH: List of SVHC
'amyl nitrite', mixed isomers	203-770-8	110-46-3	Flam. Liq. 2; Acute Tox. 4		Details
((4-phenylbutyl)hydroxyphosphoryl)acetic acid SQ 26999	412-170-7	83623-61-4	STOT RE 2; Eye Dam. 1; Skin Sens. 1		Details
(+)-(1S, 2S, 3S, 5R)-2,6,6-trimethylbicyclo[3.1.1]heptane-3-spiro-1'-(cyclohex-2'-en-4'-one)	430-460-1	133636-82-5	Skin Corr. 1B; Skin Sens. 1		Details
(+/-)-(R,R)-6-fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran; 6-fluoro-2-(2-oxiranyl)chromane	606-373-1	197706-50-6	Skin Sens. 1		Details
(-)(3S, 4R)-4-(4-fluorophenyl)-3-(3,4-methylenedioxy-phenoxymethyl)-N-benzylpiperidine hydrochloride	432-360-3	105813-13-6	Acute Tox. 4; Skin Sens. 1		Details
(-)-trans-4-(4'-fluorophenyl)-3-hydroxymethyl-N-methylpiperidine BRL 29226	406-030-4	105812-81-5	Acute Tox. 4; Eye Dam. 1		Details
(1,3,4,5,6,7-hexahydro-1,3-dioxo-2H-isoindol-2-yl)methyl (1R-trans)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate	214-619-0	1166-46-7	Carc. 2; Acute Tox. 4; STOT SE 2		Details
(1-hydroxydodecylidene)diphosphonic acid KELCOR; LIPOKEL; SEQUOL	425-230-2	16610-63-2	Skin Corr. 1B		Details
(1-methyl-1,2-ethanediyl)bis[oxy(methyl-2,1-ethanediyl)] diacrylate	256-032-2	42978-66-5	Eye Irrit. 2; STOT SE 3; Skin Irrit. 2; Skin Sens. 1		Details
(1R, 4R)-4-methoxy-2,2,7,7-tetramethyltricyclo(6.2.1.0(1,6))undec-5-ene	444-480-3	676125-00-1	Skin Irrit. 2		Details
(1R,2S,5R)-2-[(4-chlorophenyl)methyl]-5-propan-2-yl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	-	115850-69-6	Repr. 1B; Acute Tox. 4; STOT RE 2		Details
(1R,2S,5S)-2-[(4-chlorophenyl)methyl]-5-propan-2-yl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol	-	115937-89-8	Repr. 1B; Acute Tox. 4; STOT RE 2		Details
(1R,3E,4S)-1,7,7-trimethyl-3-(4- methylbenzylidene)bicyclo[2.2.1]heptan-2-one	-	95342-41-9		END Endocrine disrupting properties (Article 57(f) - human health)	Details
(1R,3S,7R,8R,10R,13R)-5,5,7,9,9,13-hexamethyl-4,6-dioxatetracyclo[6.5.1.01,10.03,7]tetradecane	427-580-1	211299-54-6	Skin Irrit. 2		Details
(1R,3Z,4S)-1,7,7-trimethyl-3-(4- methylbenzylidene)bicyclo[2.2.1]heptan-2-one	-	852541-21-0		END Endocrine disrupting properties (Article 57(f) - human health)	Details
(1R,4S)-1,7,7-trimethyl-3-(4-methylbenzylidene)bicyclo[2.2.1]heptan-2-one	-	741687-98-9		END Endocrine disrupting properties (Article 57(f) - human health)	Details
(1R,4S)-2-azabicyclo[2.2.1]hept-5-en-3-one 1418U90	418-530-1	79200-56-9	Acute Tox. 4; Eye Dam. 1; Skin Sens. 1		Details
(1S)-2-methyl-2,5-diazobicyclo[2.2.1]heptanes dihydrobromide CP-84,203-4; DFX-5S	411-000-9	125224-62-6	Skin Sens. 1		Details
(1S,2S,5R,6R,9S,10S,13R,14R)-1,6,7,8,9,14,15,16,17,17,18,18-Dodecachloropentacyclo[12.2.1.1⁶,⁹.0²,¹³.0⁵,¹⁰]octadeca-7,15-diene	-	135821-03-3		VPVB very Persistent and very Bioaccumulative (article 57e)	Details
(1S,2S,5S,6S,9R,10R,13R,14R)-1,6,7,8,9,14,15,16,17,17,18,18-Dodecachloropentacyclo[12.2.1.1⁶,⁹.0²,¹³.0⁵,¹⁰]octadeca-7,15-diene	-	135821-74-8		VPVB very Persistent and very Bioaccumulative (article 57e)	Details
(1S,3E,4R)-1,7,7-trimethyl-3-(4- methylbenzylidene)bicyclo[2.2.1]heptan-2-one	-	852541-30-1		END Endocrine disrupting properties (Article 57(f) - human health)	Details
(1S,3S,5R,6R)-(4-nitrophenylmethyl)-1-dioxo-6-phenylacetamido-penam-3-carboxylate P-NITROBENZYLESTER PGSO	412-670-5	54275-93-3	Resp. Sens. 1		Details
(1S,3Z,4R)-1,7,7-trimethyl-3-(4-methylbenzylidene)bicyclo[2.2.1]heptan-2-one	-	852541-25-4		END Endocrine disrupting properties (Article 57(f) - human health)	Details
(1S,4R,6R,7R)-(4-nitrophenylmethyl)3-methylene-1-oxo-7-phenylacetamido-cepham-4-carboxylateido-penam-3-carboxylate G-EXOMETHYLENE SULFOXIDE ESTER	412-800-0	76109-32-5	Resp. Sens. 1		Details
(1S-cis)-4-(2-amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol hydrochloride	426-200-1	172015-79-1	STOT RE 1; Acute Tox. 4; Eye Dam. 1; Skin Sens. 1		Details
(1S-cis)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine 2-hydroxy-2-phenylacetate SERTRALINE STEP 2	420-560-3	79617-97-3	Eye Dam. 1		Details
(1α,2α,3β,6β)-1,2,3,6-tetrahydro-3,6-methanophthalic anhydride	220-384-5	2746-19-2	Eye Dam. 1; Resp. Sens. 1; Skin Sens. 1		Details
(1α5α6α)-6-nitro-3-benzyl-3-azabicyclo[3.1.0]hexane methanesulfonate salt CP-141,845-27	426-740-8	256369-40-1	Acute Tox. 4; Eye Dam. 1		Details
(2,2'-(3,3'-dioxidobiphenyl-4,4'-diyldiazo)bis(6-(4-(3-(diethylamino)propylamino)-6-(-3-(diethylammonio)propylamino)1,3,5-triazin-2-ylamino)-3-sulfonato-1-naphtholato))dicopper(II) acetate lactate BLUE 10 25 964	407-240-9	159604-94-1	Skin Sens. 1		Details
(2,3,5,6-tetrafluorophenyl)methanol	443-840-7	4084-38-2	Acute Tox. 4; Eye Irrit. 2; Skin Sens. 1		Details
(2,3-dimethylbut-2-yl)-trimethoxysilane	439-360-2	142877-45-0	Skin Irrit. 2; Eye Dam. 1		Details
(2,4-diaminopteridin-6-yl)methanol hydrobromide	430-620-0	76145-91-0	STOT RE 2; Skin Sens. 1		Details
(2,5-dioxopyrrolidin-1-yl)-9H-fluoren-9-ylmethyl carbonate	433-520-5	82911-69-1	Acute Tox. 4; Skin Sens. 1		Details
(2,6-xylyloxy) acetic acid	430-910-7	13335-71-2	Acute Tox. 4; Eye Dam. 1		Details
(2-(1,3-dioxolan-2-yl)ethyl)triphenylphosphonium bromide DWS	404-940-6	86608-70-0	Acute Tox. 4; Eye Dam. 1; STOT RE 2		Details
(2-(aminomethyl)phenyl)acetylchloride hydrochloride X-17-17	417-410-4	61807-67-8	Acute Tox. 4; Skin Corr. 1A; Skin Sens. 1		Details
(2-butyl-5-nitrobenzofuran-3-yl)[4-(3-dibutylaminopropoxy)phenyl]methanone BUTAMINONITRODARONE; SR33581	444-800-1	141645-23-0	Flam. Liq. 3; Acute Tox. 4; STOT RE 2; Skin Irrit. 2; Eye Dam. 1; Skin Sens. 1		Details
(2-chloroethyl)(3-hydroxypropyl)ammonium chloride CLETOPROPAMINHYDROCHLORID	429-740-6	40722-80-3	Carc. 1B; Muta. 1B; STOT RE 2; Skin Sens. 1		Details
(2-ethylhexanoato-O)(isodecanoato-O)nickel	284-351-7	84852-39-1	Carc. 1A; Muta. 2; Repr. 1B; STOT RE 1; Resp. Sens. 1; Skin Sens. 1		Details
(2-ethylhexanoato-O)(isononanoato-O)nickel	287-470-2	85508-45-8	Carc. 1A; Muta. 2; Repr. 1B; STOT RE 1; Resp. Sens. 1; Skin Sens. 1		Details
(2-methylpropyl)lithium; isobutyllithium	440-620-2	920-36-5	Water-react. 1; Pyr. Liq. 1; Skin Corr. 1A; STOT SE 3		Details
(2E)-2-cyano-N-[(ethylamino)carbonyl]-2-(methoxyimino) acetamide	-	166900-80-7	Repr. 2; Acute Tox. 4; STOT RE 2; Skin Sens. 1		Details
(2E)-3-phenylprop-2-enal	604-377-8	14371-10-9	Skin Sens. 1A		Details
(2R)-2-amino-2-phenylacetamide	420-370-0	6485-67-2	Eye Irrit. 2; Skin Sens. 1		Details
(2R)-3-(4-tert-Butylphenyl)-2-methylpropanal	-	75166-31-3		R Toxic for reproduction (article 57c)	Details
(2R)-butan-2-amine	236-232-6	13250-12-9	Flam. Liq. 2; Acute Tox. 4; Skin Corr. 1A		Details
(2R, 3S)-2-(2,4-difluorophenyl)-3-(5-fluoro-4-pyrimidinyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol (1R)-10-camphorsulfonate UK-103,449-BV	427-100-0	-	Acute Tox. 4; Eye Dam. 1; Skin Sens. 1		Details
(2R, 3S, 4R, 5R, 7R, 9R, 10R,11S, 12S, 13R)-10-[(4-dimethylamino-3-hydroxy-6-methyltetrahydropyran-2-yl)oxy]-2-ethyl-3,4,12-trihydroxy-9-methoxy-3,5,7,9,11,13-hexamethyl-6,14-dioxo-1-oxacyclotetradecane	433-820-6	118058-74-5	Eye Irrit. 2		Details
(2R,3R)-3-((R)-1-(tert-butyldimethylsiloxy)ethyl)-4-oxoazetidin-2-yl acetate 4-AA; AOSA; AZETIDONE-KANEKA; GR91990X	408-050-9	76855-69-1	Eye Irrit. 2; Skin Sens. 1		Details
(2R,3S)-N-(3-amino-2-hydroxy-4-phenylbutyl)-N-isobutyl-4-nitrobenzenesulfonamide hydrochloride	425-260-6	244634-31-9	STOT RE 2; Eye Dam. 1; Skin Sens. 1		Details

Viser 1 - 50 af 4.917 resultater.

Export search results to:

EU-MEDICAL_DEVICES_REGULATION-ANX_I_SEC_10

EU-MEDICAL_DEVICES_REGULATION-ANX_I_SEC_10

Medical Devices Regulation - Hazardous Substances

EU. Hazardous Substances for Purposes of Medical Devices Regulation 2017/745/EU, 5 May 2017, as amended by Regulation 2020/561/EU, 24 April 2020

RELEVANT LEGISLATION

Contact EUCLEF Helpdesk

Contact Helpdesk

Last updated 28 juni 2024. Database contains 4917 unique substances/entries.

Footer Nav Items