Candidate List of substances of very high concern for Authorisation
Candidate List of substances of very high concern for Authorisation
(published in accordance with Article 59(10) of the REACH Regulation)
Candidate List of substances of very high concern for Authorisation
Notes:
- Authentic version: Only the Candidate List published on this website is deemed authentic. Companies may have immediate legal obligations following the inclusion of a substance in the Candidate List on this website including in particular Articles 7, 31 and 33 of the REACH Regulation.
- Numerical identifiers: Each candidate list entry covers both anhydrous and hydrated forms of a substance. The CAS number shown in an entry is typically for the anhydrous form. Hydrated forms of the substance identified by other CAS numbers are still within the scope of the entry.
- Other numerical identifiers: For those entries with "-" in the EC number and CAS number columns, a non-exhaustive inventory of EC and/or CAS Registry numbers describing substances or groups of substances considered to fall within the scope of the Candidate List entry is included, where practicably possible. This information can be accessed through the "Details" button of the selected entry.
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Decision | IUCLID dataset | ||||||
---|---|---|---|---|---|---|---|
200-755-8
|
71-48-7
|
15-Dec-2010
|
Carcinogenic (Article 57a) Toxic for reproduction (Article 57c) |
Details | |||
200-679-5
|
68-12-2
|
19-Dec-2012
|
Toxic for reproduction (Article 57c) |
Details | |||
200-589-6
|
64-67-5
|
19-Dec-2012
|
Carcinogenic (Article 57a) Mutagenic (Article 57b) |
Details | |||
200-453-6
|
60-09-3
|
19-Dec-2012
|
Carcinogenic (Article 57a) |
Details | |||
200-280-6
|
56-55-3
|
15-Jan-2018
|
Carcinogenic (Article 57a) PBT (Article 57d) vPvB (Article 57e) |
Details | |||
200-268-0
|
56-35-9
|
28-Oct-2008
|
PBT (Article 57d) |
Details | |||
200-028-5
|
50-32-8
|
20-Jun-2016
|
Carcinogenic (Article 57a) Mutagenic (Article 57b) Toxic for reproduction (Article 57c) PBT (Article 57d) vPvB (Article 57e) |
Details | |||
are fibres covered by index number 650-017-00-8 in Annex VI, part 3, table 3.1 of Regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labelling and packaging of substances and mixtures, and fulfil the three following conditions: a) oxides of aluminium, silicon and zirconium are the main components present (in the fibres) within variable concentration ranges b) fibres have a length weighted geometric mean diameter less two standard geometric errors of 6 or less micrometres (µm). c) alkaline oxide and alkali earth oxide (Na2O+K2O+CaO+MgO+BaO) content less or equal to 18% by weight
show/hide
|
-
|
-
|
19-Dec-2011
|
Carcinogenic (Article 57a) |
Details | ||
show/hide
|
-
|
-
|
16-Jul-2019
|
Endocrine disrupting properties (Article 57(f) - environment) |
Details | ||
show/hide
Borate(2-), tetrahydroxybis[μ-(peroxy-κO1:κO2)]di-, sodium, hydrate (1:2:6)
EC No.:
-
| CAS No.:
125022-34-6
|
-
|
-
|
16-Jun-2014
|
Toxic for reproduction (Article 57c) |
Details | ||
with ≥0.1% w/w 4-heptylphenol, branched and linear (4-HPbl)
show/hide
Reaction product of 1,3,4-thiadiazolidine-2,5-dithione, formaldehyde and phenol, heptyl derivs.
EC No.:
-
| CAS No.:
1471311-26-8
Formaldehyde, reaction products with branched and linear heptylphenol, carbon disulfide and hydrazine
EC No.:
300-298-5
| CAS No.:
93925-00-9
|
-
|
-
|
15-Jan-2018
|
Endocrine disrupting properties (Article 57(f) - environment) |
Details | ||
-
|
-
|
17-Dec-2014
|
Toxic for reproduction (Article 57c) |
Details | |||
show/hide
|
-
|
-
|
08-Jul-2021
|
Toxic for reproduction (Article 57c) Endocrine disrupting properties (Article 57(f) - environment) Endocrine disrupting properties (Article 57(f) - human health) |
Details | ||
show/hide
|
-
|
-
|
17-Dec-2015
|
Toxic for reproduction (Article 57c) PBT (Article 57d) |
Details | ||
PFHxS
show/hide
tridecafluorohexanesulphonic acid, compound with 2,2'-iminodiethanol (1:1)
EC No.:
274-462-9
| CAS No.:
70225-16-0
Phosphonium, triphenyl(phenylmethyl)-, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonate (1:1)
EC No.:
-
| CAS No.:
1000597-52-3
Ethanaminium, N-[4-[[4-(diethylamino)phenyl][4-(ethylamino)-1-naphthalenyl]methylene]-2,5-cyclohexadien-1-ylidene]-N-ethyl-, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonate (1:1)
EC No.:
-
| CAS No.:
1310480-24-0
Methanaminium, N-[4-[[4-(dimethylamino)phenyl][4-(ethylamino)-1-naphthalenyl]methylene]-2,5-cyclohexadien-1-ylidene]-N-methyl-, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonate (1:1)
EC No.:
-
| CAS No.:
1310480-27-3
Methanaminium, N-[4-[[4-(dimethylamino)phenyl][4-(phenylamino)-1-naphthalenyl]methylene]-2,5-cyclohexadien-1-ylidene]-N-methyl-, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonate (1:1)
EC No.:
-
| CAS No.:
1310480-28-4
Beta-Cyclodextrin, compd. with 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonic acid ion(1-)(1:1)
EC No.:
-
| CAS No.:
1329995-45-0
Gamma-Cyclodextrin, compd. with 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonic acid ion(1-)(1:1)
EC No.:
-
| CAS No.:
1329995-69-8
Sulfonium, triphenyl-, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonate (1:1)
EC No.:
-
| CAS No.:
144116-10-9
Quinolinium, 1-(carboxymethyl)-4-[2-[4-[4-(2,2-diphenylethenyl)phenyl]-1,2,3,3a,4,8b-hexahydrocyclopent[b]indol-7-yl]ethenyl]-, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonate (1:1)
EC No.:
-
| CAS No.:
1462414-59-0
Iodonium, diphenyl-, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonate (1:1)
EC No.:
-
| CAS No.:
153443-35-7
Methanaminium, N,N,N-trimethyl-, salt with 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonic acid (1:1)
EC No.:
-
| CAS No.:
189274-31-5
1-Hexanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-, compd.with 2-methyl-2-propanamine (1:1)
EC No.:
-
| CAS No.:
202189-84-2
Iodonium, bis[4-(1,1-dimethylethyl)phenyl]-, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonate (1:1)
EC No.:
-
| CAS No.:
213740-81-9
1-Hexanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-, gallium salt (9CI)
EC No.:
-
| CAS No.:
341035-71-0
Sulfonium, bis(4-methylphenyl)phenyl-, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonate (1:1)
EC No.:
-
| CAS No.:
341548-85-4
1-Hexanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-, scandium(3+) salt (3:1)
EC No.:
-
| CAS No.:
350836-93-0
1-Hexanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-, neodymium(3+) salt (3:1)
EC No.:
-
| CAS No.:
41184-65-0
1-Hexanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-, yttrium(3+) salt (3:1)
EC No.:
-
| CAS No.:
41242-12-0
Sulfonium, (thiodi-4,1-phenylene)bis[diphenyl-, salt with 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonic acid (1:2)
EC No.:
-
| CAS No.:
421555-73-9
Iodonium, bis[4-(1,1-dimethylpropyl)phenyl]-, salt with 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonic
EC No.:
-
| CAS No.:
421555-74-0
Sulfonium, tris[4-(1,1-dimethylethyl)phenyl]-, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonate (1:1)
EC No.:
-
| CAS No.:
425670-70-8
1-Hexanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-, lithium salt (1:1)
EC No.:
-
| CAS No.:
55120-77-9
1-Hexanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-, zinc salt
EC No.:
-
| CAS No.:
70136-72-0
1-Hexanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-, compd. with N,N-diethylethanamine (1:1)
EC No.:
-
| CAS No.:
72033-41-1
1-Hexanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-, sodium salt
EC No.:
-
| CAS No.:
82382-12-5
Iodonium, bis[(1,1-dimethylethyl)phenyl]-, salt with 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonic acid (1:1) (9CI)
EC No.:
-
| CAS No.:
866621-50-3
Sulfonium, (4-methylphenyl)diphenyl-, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonate (1:1)
EC No.:
-
| CAS No.:
910606-39-2
Sulfonium, [4-[(2-methyl-1-oxo-2-propen-1-yl)oxy]phenyl]diphenyl-, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonate (1:1)
EC No.:
-
| CAS No.:
911027-68-4
Dibenzo[k,n][1,4,7,10,13]tetraoxathiacyclopentadecinium, 19-[4-(1,1-dimethylethyl)phenyl]-6,7,9,10,12,13-hexahydro-, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-1-hexanesulfonate (1:1)
EC No.:
-
| CAS No.:
928049-42-7
1-Hexanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-, cesium salt (1:1)
EC No.:
-
| CAS No.:
92011-17-1
1-Hexanesulfonic acid, 1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluoro-, compd. With pyrrolidine (1:1)
EC No.:
-
| CAS No.:
1187817-57-7
|
-
|
-
|
07-Jul-2017
|
vPvB (Article 57e) |
Details | ||
show/hide
|
-
|
-
|
17-Jan-2023
|
Toxic for reproduction (Article 57c) PBT (Article 57d) vPvB (Article 57e) Equivalent level of concern having probable serious effects to human health (Article 57(f) - human health) Equivalent level of concern having probable serious effects to the environment (Article 57(f) - environment) |
Details | ||
show/hide
1-(4-butoxy-1-naphthalenyl)tetrahydrothiophenium 1,1,2,2,3,3,4,4,4-nonafluoro-1-butanesulfonate
EC No.:
468-770-4
| CAS No.:
-
N,N,N-triethylethanaminium 1,1,2,2,3,3,4,4,4-nonafluorobutane-1-sulfonate
EC No.:
-
| CAS No.:
25628-08-4
|
-
|
-
|
16-Jan-2020
|
Equivalent level of concern having probable serious effects to human health (Article 57(f) - human health) Equivalent level of concern having probable serious effects to the environment (Article 57(f) - environment) |
Details | ||
show/hide
|
-
|
-
|
08-Jul-2021
|
Toxic for reproduction (Article 57c) |
Details | ||
show/hide
|
-
|
-
|
12-Jan-2017
|
Toxic for reproduction (Article 57c) PBT (Article 57d) |
Details | ||
-
|
776297-69-9
|
19-Dec-2012
|
Toxic for reproduction (Article 57c) |
Details | |||
UVCB substances consisting of more than or equal to 80% linear chloroalkanes with carbon chain lengths within the range from C14 to C17
show/hide
|
-
|
-
|
08-Jul-2021
|
PBT (Article 57d) vPvB (Article 57e) |
Details | ||
including cis- and trans- stereo isomeric forms and all possible combinations of the isomers
show/hide
|
-
|
-
|
19-Dec-2012
|
Respiratory sensitising properties (Article 57(f) - human health) |
Details | ||
and all major diastereoisomers identified
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|
-
|
-
|
28-Oct-2008
|
PBT (Article 57d) |
Details | ||
show/hide
|
-
|
-
|
19-Jan-2021
|
Toxic for reproduction (Article 57c) |
Details | ||
all possible combinations of the cis- and trans-isomers
show/hide
|
-
|
-
|
19-Dec-2012
|
Respiratory sensitising properties (Article 57(f) - human health) |
Details | ||
EC No. 233-139-2 and EC No. 234-343-4
show/hide
|
-
|
-
|
18-Jun-2010
|
Toxic for reproduction (Article 57c) |
Details | ||
show/hide
|
-
|
-
|
17-Jan-2023
|
vPvB (Article 57e) |
Details | ||
are fibres covered by index number 650-017-00-8 in Annex VI, part 3, table 3.1 of Regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labelling and packaging of substances and mixtures, and fulfil the three following conditions: a) oxides of aluminium and silicon are the main components present (in the fibres) within variable concentration ranges b) fibres have a length weighted geometric mean diameter less two standard geometric errors of 6 or less micrometres (µm) c) alkaline oxide and alkali earth oxide (Na2O+K2O+CaO+MgO+BaO) content less or equal to 18% by weight
show/hide
|
-
|
-
|
19-Dec-2011
|
Carcinogenic (Article 57a) |
Details | ||
show/hide
|
-
|
-
|
15-Dec-2010
|
Carcinogenic (Article 57a) |
Details | ||
covering any of the individual stereoisomers of [1] and [2] or any combination thereof
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1,3-Dioxane, 2-[(1S,2S)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, trans-
EC No.:
-
| CAS No.:
676367-06-9
Reaction mass of 5-sec-butyl-2-(2,4-dimethylcyclohex-3-en-1-yl)-5-methyl-1,3-dioxane and 5-sec-butyl-2-(4,6-dimethylcyclohex-3-en-1-yl)-5-methyl-1,3-dioxane
EC No.:
413-720-9
| CAS No.:
-
1,3-Dioxane, 2-(2,4-dimethyl-3-cyclohexen-1-yl)-5-methyl-5-(1-methylpropyl)-
EC No.:
-
| CAS No.:
117933-89-8
1,3-Dioxane, 2-(2,4-dimethyl-3-cyclohexen-1-yl)-5-methyl-5-(1-methylpropyl)-
EC No.:
-
| CAS No.:
186309-28-4
1,3-Dioxane, 2-[(1R,2R)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, cis-
EC No.:
-
| CAS No.:
676367-05-8
1,3-Dioxane, 2-[(1R,2R)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, cis-rel-
EC No.:
-
| CAS No.:
343934-04-3
1,3-Dioxane, 2-[(1R,2R)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, trans-
EC No.:
-
| CAS No.:
676367-09-2
1,3-Dioxane, 2-[(1R,2R)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, trans-rel-
EC No.:
-
| CAS No.:
343934-05-4
1,3-Dioxane, 2-[(1R,2S)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, cis-
EC No.:
-
| CAS No.:
676367-04-7
1,3-Dioxane, 2-[(1R,2S)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, trans-
EC No.:
-
| CAS No.:
676367-08-1
1,3-Dioxane, 2-[(1S,2R)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, cis-
EC No.:
-
| CAS No.:
676367-03-6
1,3-Dioxane, 2-[(1S,2R)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, trans-
EC No.:
-
| CAS No.:
676367-07-0
1,3-Dioxane, 2-[(1S,2S)-2,4-dimethyl-3-cyclohexen-1-yl]-5-methyl-5-(1-methylpropyl)-, cis-
EC No.:
-
| CAS No.:
676367-02-5
|
-
|
-
|
15-Jun-2015
|
vPvB (Article 57e) |
Details | ||
substances with a linear and/or branched alkyl chain with a carbon number of 9 covalently bound in position 4 to phenol, covering also UVCB- and well-defined substances which include any of the individual isomers or a combination thereof
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|
-
|
-
|
19-Dec-2012
|
Endocrine disrupting properties (Article 57(f) - environment) |
Details | ||
substances with a linear and/or branched alkyl chain with a carbon number of 7 covalently bound predominantly in position 4 to phenol, covering also UVCB- and well-defined substances which include any of the individual isomers or a combination thereof
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|
-
|
-
|
12-Jan-2017
|
Endocrine disrupting properties (Article 57(f) - environment) |
Details | ||
covering well-defined substances and UVCB substances, polymers and homologues
show/hide
20-[4-(1,1,3,3-tetramethylbutyl)phenoxy]-3,6,9,12,15,18-hexaoxaicosan-1-ol
EC No.:
219-682-8
| CAS No.:
2497-59-8
Poly(oxy-1,2-ethanediyl), α-[(1,1,3,3-tetramethylbutyl)phenyl]-ω-hydroxy-
EC No.:
-
| CAS No.:
9036-19-5
|
-
|
-
|
19-Dec-2012
|
Endocrine disrupting properties (Article 57(f) - environment) |
Details | ||
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|
-
|
-
|
19-Dec-2012
|
Carcinogenic (Article 57a) Mutagenic (Article 57b) |
Details | ||
show/hide
|
-
|
-
|
08-Jul-2021
|
Toxic for reproduction (Article 57c) |
Details | ||
covering any of their individual isomers and combinations thereof
show/hide
potassium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propionate
EC No.:
266-578-3
| CAS No.:
67118-55-2
|
-
|
-
|
16-Jul-2019
|
Equivalent level of concern having probable serious effects to human health (Article 57(f) - human health) Equivalent level of concern having probable serious effects to the environment (Article 57(f) - environment) |
Details | ||
show/hide
|
-
|
-
|
08-Jul-2021
|
Carcinogenic (Article 57a) |
Details | ||
covering any of its individual anti- and syn-isomers or any combination thereof
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(1S,2S,5R,6R,9S,10S,13R,14R)-1,6,7,8,9,14,15,16,17,17,18,18-Dodecachloropentacyclo[12.2.1.1⁶,⁹.0²,¹³.0⁵,¹⁰]octadeca-7,15-diene
EC No.:
-
| CAS No.:
135821-03-3
(1S,2S,5S,6S,9R,10R,13R,14R)-1,6,7,8,9,14,15,16,17,17,18,18-Dodecachloropentacyclo[12.2.1.1⁶,⁹.0²,¹³.0⁵,¹⁰]octadeca-7,15-diene
EC No.:
-
| CAS No.:
135821-74-8
1,6,7,8,9,14,15,16,17,17,18,18-dodecachloropentacyclo[12.2.1.16,9.02,13.05,10]octadeca-7,15-diene
EC No.:
236-948-9
| CAS No.:
13560-89-9
|
-
|
-
|
15-Jan-2018
|
vPvB (Article 57e) |
Details | ||
with ≥ 0.3% of dihexyl phthalate (EC No. 201-559-5)
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1,2-Benzenedicarboxylic acid, mixed decyl and hexyl and octyl diesters
EC No.:
272-013-1
| CAS No.:
68648-93-1
|
-
|
-
|
15-Jun-2015
|
Toxic for reproduction (Article 57c) |
Details | ||
show/hide
(±)-1,7,7-trimethyl-3-[(4-methylphenyl)methylene]bicyclo[2.2.1]heptan-2-one
EC No.:
253-242-6
| CAS No.:
36861-47-9
(3E)-1,7,7-trimethyl-3-(4-methylbenzylidene)bicyclo[2.2.1]heptan-2-one
EC No.:
-
| CAS No.:
1782069-81-1
(1R,3E,4S)-1,7,7-trimethyl-3-(4-methylbenzylidene)bicyclo[2.2.1]heptan-2-one
EC No.:
-
| CAS No.:
95342-41-9
(1S,3E,4R)-1,7,7-trimethyl-3-(4-methylbenzylidene)bicyclo[2.2.1]heptan-2-one
EC No.:
-
| CAS No.:
852541-30-1
(1R,3Z,4S)-1,7,7-trimethyl-3-(4-methylbenzylidene)bicyclo[2.2.1]heptan-2-one
EC No.:
-
| CAS No.:
852541-21-0
(1R,4S)-1,7,7-trimethyl-3-(4-methylbenzylidene)bicyclo[2.2.1]heptan-2-one
EC No.:
-
| CAS No.:
741687-98-9
(1S,3Z,4R)-1,7,7-trimethyl-3-(4-methylbenzylidene)bicyclo[2.2.1]heptan-2-one
EC No.:
-
| CAS No.:
852541-25-4
|
-
|
-
|
17-Jan-2022
|
Endocrine disrupting properties (Article 57(f) - human health) |
Details | ||