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Candidate List of substances of very high concern for Authorisation

Candidate List of substances of very high concern for Authorisation

(published in accordance with Article 59(10) of the REACH Regulation)

Candidate List of substances of very high concern for Authorisation

Notes:

  • Authentic version: Only the Candidate List published on this website is deemed authentic. Companies may have immediate legal obligations following the inclusion of a substance in the Candidate List on this website including in particular Articles 7, 31 and 33 of the REACH Regulation.
  • Numerical identifiers: Each candidate list entry covers both anhydrous and hydrated forms of a substance. The CAS number shown in an entry is typically for the anhydrous form. Hydrated forms of the substance identified by other CAS numbers are still within the scope of the entry.
  • Other numerical identifiers: For those entries with "-" in the EC number and CAS number columns, a non-exhaustive inventory of EC and/or CAS Registry numbers describing substances or groups of substances considered to fall within the scope of the Candidate List entry is included, where practicably possible. This information can be accessed through the "Details" button of the selected entry. 
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Substance name
EC No.
CAS No.
Date of inclusion
Reason for inclusion
Decision IUCLID dataset  
(±)-1,7,7-trimethyl-3-[(4-methylphenyl)methylene]bicyclo[2.2.1]heptan-2-one covering any of the individual isomers and/or combinations thereof (4-MBC)
show/hide
(±)-1,7,7-trimethyl-3-[(4-methylphenyl)methylene]bicyclo[2.2.1]heptan-2-one EC No.: 253-242-6 | CAS No.: 36861-47-9
(3E)-1,7,7-trimethyl-3-(4-methylbenzylidene)bicyclo[2.2.1]heptan-2-one EC No.: - | CAS No.: 1782069-81-1
(1R,3E,4S)-1,7,7-trimethyl-3-(4-methylbenzylidene)bicyclo[2.2.1]heptan-2-one EC No.: - | CAS No.: 95342-41-9
(1S,3E,4R)-1,7,7-trimethyl-3-(4-methylbenzylidene)bicyclo[2.2.1]heptan-2-one EC No.: - | CAS No.: 852541-30-1
(1R,3Z,4S)-1,7,7-trimethyl-3-(4-methylbenzylidene)bicyclo[2.2.1]heptan-2-one EC No.: - | CAS No.: 852541-21-0
(1R,4S)-1,7,7-trimethyl-3-(4-methylbenzylidene)bicyclo[2.2.1]heptan-2-one EC No.: - | CAS No.: 741687-98-9
(1S,3Z,4R)-1,7,7-trimethyl-3-(4-methylbenzylidene)bicyclo[2.2.1]heptan-2-one EC No.: - | CAS No.: 852541-25-4
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17-Jan-2022
Endocrine disrupting properties (Article 57(f) - human health)
D(2021)10043-DC
Details
1,2-benzenedicarboxylic acid, di-C6-10-alkyl esters or mixed decyl and hexyl and octyl diesters
with ≥ 0.3% of dihexyl phthalate (EC No. 201-559-5)
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1,2-Benzenedicarboxylic acid, mixed decyl and hexyl and octyl diesters EC No.: 272-013-1 | CAS No.: 68648-93-1
1,2-Benzenedicarboxylic acid, di-C6-10-alkyl esters EC No.: 271-094-0 | CAS No.: 68515-51-5
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15-Jun-2015
Toxic for reproduction (Article 57c)
ED/39/2015


Details
1,6,7,8,9,14,15,16,17,17,18,18-Dodecachloropentacyclo[12.2.1.16,9.02,13.05,10]octadeca-7,15-diene (“Dechlorane Plus”™)
covering any of its individual anti- and syn-isomers or any combination thereof
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(1S,2S,5R,6R,9S,10S,13R,14R)-1,6,7,8,9,14,15,16,17,17,18,18-Dodecachloropentacyclo[12.2.1.1⁶,⁹.0²,¹³.0⁵,¹⁰]octadeca-7,15-diene EC No.: - | CAS No.: 135821-03-3
(1S,2S,5S,6S,9R,10R,13R,14R)-1,6,7,8,9,14,15,16,17,17,18,18-Dodecachloropentacyclo[12.2.1.1⁶,⁹.0²,¹³.0⁵,¹⁰]octadeca-7,15-diene EC No.: - | CAS No.: 135821-74-8
1,6,7,8,9,14,15,16,17,17,18,18-dodecachloropentacyclo[12.2.1.16,9.02,13.05,10]octadeca-7,15-diene EC No.: 236-948-9 | CAS No.: 13560-89-9
rel-(1R,4S,4aS,6aS,7S,10R,10aR,12aR)-1,2,3,4,7,8,9,10,13,13,14,14-dodecachloro-1,4,4a,5,6,6a,7,10,10a,11,12,12a-dodecahydro-1,4:7,10-dimethanodibenzo[a,e]cyclooctene EC No.: - | CAS No.: -
rel-(1R,4S,4aS,6aR,7R,10S,10aS,12aR)-1,2,3,4,7,8,9,10,13,13,14,14-dodecachloro-1,4,4a,5,6,6a,7,10,10a,11,12,12a-dodecahydro-1,4:7,10-dimethanodibenzo[a,e]cyclooctene EC No.: - | CAS No.: -
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15-Jan-2018
vPvB (Article 57e)
ED/01/2018
Details
2,2-bis(bromomethyl)propane-1,3-diol (BMP); 2,2-dimethylpropan-1-ol, tribromo derivative/3-bromo-2,2-bis(bromomethyl)-1-propanol (TBNPA); 2,3-dibromo-1-propanol (2,3-DBPA)
show/hide
2,2-bis(bromomethyl)propane-1,3-diol (BMP) EC No.: 221-967-7 | CAS No.: 3296-90-0
2,2-dimethylpropan-1-ol, tribromo derivative (TBNPA) EC No.: 253-057-0 | CAS No.: 36483-57-5
3-bromo-2,2-bis(bromomethyl)-1-propanol (TBNPA) EC No.: - | CAS No.: 1522-92-5
2,3-dibromo-1-propanol (2,3-DBPA) EC No.: 202-480-9 | CAS No.: 96-13-9
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08-Jul-2021
Carcinogenic (Article 57a)
D(2021)4569-DC
Details
2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propionic acid, its salts and its acyl halides
covering any of their individual isomers and combinations thereof
show/hide
ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoate EC No.: - | CAS No.: 62037-80-3
2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propionyl fluoride EC No.: 218-173-8 | CAS No.: 2062-98-8
2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propionic acid EC No.: 236-236-8 | CAS No.: 13252-13-6
potassium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propionate EC No.: 266-578-3 | CAS No.: 67118-55-2
Propanoic acid, 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-, (+)- EC No.: - | CAS No.: 75579-39-4
Propanoic acid, 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-, (-)- EC No.: - | CAS No.: 75579-40-7
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16-Jul-2019
Equivalent level of concern having probable serious effects to human health (Article 57(f) - human health)
Equivalent level of concern having probable serious effects to the environment (Article 57(f) - environment)
ED/71/2019
Details
2-(4-tert-butylbenzyl)propionaldehyde and its individual stereoisomers
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2-(4-tert-butylbenzyl)propionaldehyde EC No.: 201-289-8 | CAS No.: 80-54-6
(2S)-3-(4-tert-butylphenyl)-2-methylpropanal EC No.: - | CAS No.: 75166-30-2
(2R)-3-(4-tert-butylphenyl)-2-methylpropanal EC No.: - | CAS No.: 75166-31-3
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08-Jul-2021
Toxic for reproduction (Article 57c)
D(2021)4569-DC.pdf
Details
4,4'-oxydianiline and its salts
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4,4'-oxydianiline EC No.: 202-977-0 | CAS No.: 101-80-4
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19-Dec-2012
Carcinogenic (Article 57a)
Mutagenic (Article 57b)
ED/169/2012
Details
4-(1,1,3,3-tetramethylbutyl)phenol, ethoxylated
covering well-defined substances and UVCB substances, polymers and homologues
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Poly(oxy-1,2-ethanediyl), α-[(1,1,3,3-tetramethylbutyl)phenyl]-ω-hydroxy- EC No.: - | CAS No.: 9036-19-5
Polyethylene glycol p-(1,1,3,3-tetramethylbutyl)phenyl ether EC No.: - | CAS No.: 9002-93-1
2-[4-(1,1,3,3-tetramethylbutyl)phenoxy]ethanol EC No.: - | CAS No.: 2315-67-5
2-[2-[4-(1,1,3,3-tetramethylbutyl)phenoxy]ethoxy]ethanol EC No.: - | CAS No.: 2315-61-9
20-[4-(1,1,3,3-tetramethylbutyl)phenoxy]-3,6,9,12,15,18-hexaoxaicosan-1-ol EC No.: 219-682-8 | CAS No.: 2497-59-8
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19-Dec-2012
Endocrine disrupting properties (Article 57(f) - environment)
ED/169/2012
Details
4-heptylphenol, branched and linear
substances with a linear and/or branched alkyl chain with a carbon number of 7 covalently bound predominantly in position 4 to phenol, covering also UVCB- and well-defined substances which include any of the individual isomers or a combination thereof
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Phenol, heptyl derivs. EC No.: 276-743-1 | CAS No.: 72624-02-3
4-heptylphenol EC No.: 217-862-0 | CAS No.: 1987-50-4
4-(2,3,3-trimethylbutan-2-yl)phenol EC No.: - | CAS No.: 72861-06-4
4-(2,4-dimethylpentan-2-yl)phenol EC No.: - | CAS No.: 33104-11-9
4-(3-ethylpentan-3-yl)phenol EC No.: - | CAS No.: 37872-24-5
4-(2-methylhexan-2-yl)phenol EC No.: - | CAS No.: 30784-31-7
4-(3,3-dimethylpentan-2-yl)phenol EC No.: - | CAS No.: 911371-06-7
4-(3-methylhexan-2-yl)phenol EC No.: - | CAS No.: 854904-93-1
4-(4,4-dimethylpentan-2-yl)phenol EC No.: - | CAS No.: 911371-07-8
4-(4-methylhexan-2-yl)phenol EC No.: - | CAS No.: 71945-81-8
4-(3-methylhexan-3-yl)phenol EC No.: - | CAS No.: 30784-32-8
4-(2,2-dimethylpentan-3-yl)phenol EC No.: - | CAS No.: 861010-65-3
4-(5-methylhexan-3-yl)phenol EC No.: - | CAS No.: 854904-92-0
4-(heptan-3-yl)phenol EC No.: - | CAS No.: 6465-74-3
4-(heptan-2-yl)phenol EC No.: - | CAS No.: 6863-24-7
4-(heptan-4-yl)phenol EC No.: - | CAS No.: 6465-71-0
4-(3-ethylpentyl)phenol EC No.: - | CAS No.: 911370-98-4
4-(3-methylhexyl)phenol EC No.: - | CAS No.: 102570-52-5
4-(4-methylhexyl)phenol EC No.: - | CAS No.: 1139800-98-8
4-(5-methylhexyl)phenol EC No.: - | CAS No.: 100532-36-3
4-(2,4-dimethylpentan-3-yl)phenol EC No.: - | CAS No.: 1824346-00-0
4-(2,3-dimethylpentan-2-yl)phenol EC No.: - | CAS No.: 861011-60-1
Phenol, 4-(1-ethyl-1,2-dimethylpropyl)- EC No.: - | CAS No.: 30784-27-1
Phenol, 4-tert-heptyl- EC No.: - | CAS No.: 288864-02-8
4-(5-methylhexan-2-yl)phenol EC No.: - | CAS No.: 857629-71-1
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12-Jan-2017
Endocrine disrupting properties (Article 57(f) - environment)
ED/01/2017
Details
4-Nonylphenol, branched and linear
substances with a linear and/or branched alkyl chain with a carbon number of 9 covalently bound in position 4 to phenol, covering also UVCB- and well-defined substances which include any of the individual isomers or a combination thereof
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4-(1-Ethyl-1,4-dimethylpentyl)phenol EC No.: - | CAS No.: 142731-63-3
p-(1,1-dimethylheptyl)phenol EC No.: 250-339-5 | CAS No.: 30784-30-6
p-nonylphenol EC No.: 203-199-4 | CAS No.: 104-40-5
p-(1-methyloctyl)phenol EC No.: 241-427-4 | CAS No.: 17404-66-9
Phenol, 4-nonyl-, branched EC No.: 284-325-5 | CAS No.: 84852-15-3
4-(1-ethyl-1-methylhexyl)phenol EC No.: 257-907-1 | CAS No.: 52427-13-1
p-isononylphenol EC No.: 247-770-6 | CAS No.: 26543-97-5
4-(1-Ethyl-1,3-dimethylpentyl)phenol EC No.: - | CAS No.: 186825-36-5
4-(1,1,5-Trimethylhexyl)phenol EC No.: - | CAS No.: 521947-27-3
Isononylphenol EC No.: 234-284-4 | CAS No.: 11066-49-2
4-(3-ethylheptan-2-yl)phenol EC No.: - | CAS No.: 186825-39-8
Nonylphenol EC No.: 246-672-0 | CAS No.: 25154-52-3
Phenol, nonyl-, branched EC No.: 291-844-0 | CAS No.: 90481-04-2
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19-Dec-2012
Endocrine disrupting properties (Article 57(f) - environment)
ED/169/2012
Details
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