Registration Dossier

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
0.001 mg/L
Assessment factor:
10
Extrapolation method:
assessment factor
PNEC freshwater (intermittent releases):
0.027 mg/L

Marine water

Hazard assessment conclusion:
PNEC aqua (marine water)
PNEC value:
0 mg/L
Assessment factor:
100
Extrapolation method:
assessment factor

STP

Hazard assessment conclusion:
PNEC STP
PNEC value:
0.56 mg/L
Assessment factor:
100
Extrapolation method:
assessment factor

Sediment (freshwater)

Hazard assessment conclusion:
PNEC sediment (freshwater)
PNEC value:
0.128 mg/kg sediment dw
Assessment factor:
100
Extrapolation method:
assessment factor

Sediment (marine water)

Hazard assessment conclusion:
PNEC sediment (marine water)
PNEC value:
0.013 mg/kg sediment dw
Assessment factor:
1 000
Extrapolation method:
assessment factor

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
PNEC soil
PNEC value:
2.5 mg/kg soil dw
Assessment factor:
10
Extrapolation method:
assessment factor

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
PNEC oral
PNEC value:
1.87 mg/kg food
Assessment factor:
3 000

Additional information

Conclusion on classification

Classification related key information for OPP (CAS 90-43-7):

Biodegradation in water: readily biodegradable (OECD 301B)

Bioaccumulation: no potential to bioaccumulate; BCF = 21.7

Water solubility: 0.56 g/L at 20 ºC (92/69/EEC, A.6)

 

Acute toxicity:

- For fish: 96 h LC50 (Danio rerio) = 4.5 mg/L (nominal, OECD 203)

- For invertebrates: 48 h EC50 (Daphnia magna) = 2.7 mg a.i./L (nominal, ASTM Standard E729-80)

- For algae: 72 h EC50 (Pseudokirchneriella subspicata, growth rate) = 3.57 mg a.i./L (measured, OECD 201)

 

Chronic toxicity:

- For fish: 21 d NOEC (Pimephales promelas; reproduction) = 0.036 mg a.i./L (measured)

- For invertebrates: 21 d NOEC (Daphnia magna, reproduction): = 0.009 mg a.i./L (measured, OECD 211)

- For algae: 72 h NOEC (Pseudokirchneriella subspicata, growth rate) = 0.468 mg/L (measured, OECD 201)

 

Classification justification according to CLP:

OPP (CAS-No. 90-43-7) is legally classified as Acute Cat. 1 according to Regulation (EC) No 1272/2008, Annex VI, Part 3, List of harmonised classification and labelling of hazardous substances. This is not supported with the listed key study data. Based on the chronic data, available for fish, invertebrates and algae, the lowest NOEC is 0.009 mg/L (i.e. in the rage of > 0.001 to < 0.01 mg/L) for aquatic invertebrates. Therefore, OPP needs to be additionally classified and labeled as environmental hazard Chronic Cat. 1 according to the Regulation (EC) No.1272/2008 (CLP) and the Regulation (EU) No. 286/2011 (2nd ATP).

 

M-factor for acute aquatic toxicity:  not need to be assigned

M-factor for chronic aquatic toxicity: 1