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Ecotoxicological information

Toxicity to birds

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Description of key information

OPP can be considered as non-toxic to birds

Key value for chemical safety assessment

Additional information

Toxicity to birds is not a standard requirement according to Regulation (EC) No. 1907/2006, Annex VII-IX. OPP (CAS-No. 90-43-7) is readily biodegradable with a low potential for bioaccumulation in biota (see IUCLID section 5.3) and therefore, according to the Guidance on information requirements and chemical safety assessment, Chapter R.7c, secondary poisoning is unlikely to occur (ECHA, 2008). However, additional data obtained from three tests according to US-EPA guideline 71-1 and 71-2 are available.

The results of the study carried out according to US-EPA guideline 71-1 indicate that OPP was not harmful to adult Anas platyrhynchos up to the highest tested dosage of 2250 mg a. i. /kg bw, i. e. The acute oral LD50 was determined to be > 2250 mg a. i. /kg bw (Grimes, 1986a).

In the two studies performed according to US-EPA guideline 71-2, subacute effects on Anas platyrhynchos and Colinus virginianus were investigated. No mortalities or abnormal behaviour were observed for Anas platyrhynchos (Grimes, 1986b). The LC50 value of OPP was determined to be greater than the highest concentration of 5620 mg a. i. /kg diet for Colinus virginianus, and for Anas platyrhynchos the NOEC was 3160 mg a. i. /kg diet based upon a slight reduction in body weight gain at 5620 mg a. i. /kg diet (Grimes, 1986c).

Based on the results, OPP is not expected to have effects on birds.