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EC number: 201-993-5 | CAS number: 90-43-7
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient)
- GLP compliance:
- yes
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Type:
- log Pow
- Partition coefficient:
- 2.4
- Temp.:
- 25 °C
- pH:
- 5
- Type:
- log Pow
- Partition coefficient:
- 2.5
- Temp.:
- 25 °C
- pH:
- 7
- Type:
- log Pow
- Partition coefficient:
- 2.3
- Temp.:
- 25 °C
- pH:
- 9
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient)
- GLP compliance:
- yes
- Type of method:
- flask method
- Partition coefficient type:
- octanol-water
- Type:
- log Pow
- Partition coefficient:
- 3.18
- Temp.:
- 22.5 °C
- Remarks on result:
- other: pH not reported.
Referenceopen allclose all
The Log Pow is 3.18 , no data on pH available.
Description of key information
Log Kow: 3.18 at 22.5 °C
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 3.18
- at the temperature of:
- 22.5 °C
Additional information
A log Kowvalue of 3.18 at 22.5 °C was determined by the shake-flask method according to EU Method A.8. In a supporting study by HPLC according to EU Method A.8 it is shown that the log Powvalue is not significantly influenced by the pH value when investigated at pH = 5, 7, 9 and 25 °C.
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