Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 201-557-4
CAS number: 84-74-2
A study in rabbits with undiluted DBP (OECD Guideline 404) revealed
slight erythema in 2 out of 3 animals immediately after exposure and
after 24 hours. No oedema was seen. Erythema disappeared 48 hours after
exposure. DBP was not considered a skin irritant (BASF 1990a*).
Greenough et al. (1981*) reported mild reactions 24 hours after 0.5 mL
of undiluted Vestinol C (DBP trade name) was applied to intact and
abraded rabbit skins. The positive control was reported as 10 %
laurylsulphate. No reaction was observed after 72 hours at any treatment
site. The irritation index was calculated as 0.54/8.
A study cited in an NTP-CERHR report on DBP (CERHR 2003) reported minor
irritation in rabbit dermal occlusion studies at 520 mg/kg bw/d.
Sligth skin irritation was reported, which dissappeared after 48h (study
1) or 72h (study 2).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Dan is-sit web juża l-cookies biex jiżgura li jkollok l-aqwa esperjenza fuq is-siti web tagħna.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again