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EC number: 201-557-4
CAS number: 84-74-2
In a study in rabbits with undiluted DBP (OECD Guideline 405), prominent
conjunctival redness was observed after one hour and 24 hours in all
animals, which reduced in severity after 48 hours and was completely
reversed by 72 hours. DBP was not considered an eye irritant (BASF,
Undiluted 0.1 mL of Vestinol C (trade name of DBP) was applied to rabbit
eyes (3/sex), which were not rinsed post administration. After one hour,
three out of six animals showed mild redness and the balance (three
animals) exhibited extremely mild redness. After 24 hours, very mild
redness was observed in two out of six animals. Iris or corneal effects
were not observed. The irritation index was calculated as 0.11/110. DBP
was not considered an eye irritant (Greenough et al. 1981*).
Slight reversive eye irritation was observed in both studies.
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