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EC number: 284-892-9
CAS number: 84989-04-8
The fraction of tar acid rich in 3- and 4-methylphenol, recovered by distillation of low-temperature coal tar crude tar acids.
RS-Freetext:Compound consumption:dose---------male------female[ppm]---------[mg/kg bw/d]-----------------------------5000 ---------794 -------93510000--------2723------166320000--------2723------3205
No significant elevation in the frequency of micronucleated erythrocytes
was observed in either male or female mice.
NOAEL for systemic toxicity is 1250 ppm (199 and 237 mg/kg bw/d, respectively)
based on increased relative and absolute liver and kidney weights
without histopathological correlate from 2500 ppm onwards.
Following repeated oral dosing of mice over a period of 13 weeks with
o-cresol, the MNT with peripheral erythrocytes yielded a negative result.
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