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EC number: 284-892-9
CAS number: 84989-04-8
The fraction of tar acid rich in 3- and 4-methylphenol, recovered by distillation of low-temperature coal tar crude tar acids.
doses and mortality:
215mg/kg bw: 1/5; 316 mg/kg bw: 3/5; 464 mg/Kg bw: 4/5; 681
mg/kg bw: 5/5
signs of intoxication from 4-12 hrs post appl.: tremor,
salivation sedation, death
dermal irritation: severe subdermal hemorrhaging, severe
gross autopsy: survivors: no significant findings;
inflammation of kidneys
To determine LD-50 value, rabbits received dermal application of 215
-681 mg/kg bw undiluted p-cresol and were observed for sclinical signs
of toxicity and mortality for up to 14 days: LD50 was determined 301
mg/kg bw. As signs of intoxication tremor, salivation, sedation was
noted ; the treated skin showed severe erythema and severe subdermal
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