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Ecotoxicological information

Toxicity to birds

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Description of key information

Since cresols have a low bioaccumulation potential they are not expected to accumulate in food chains and thus not to cause any adverse effect in birds.

Key value for chemical safety assessment

Additional information

No valid experimental study on toxicity of cresols to birds is available. In accordance with section 1 of REACH Annex XI, the study does not need to be conducted if testing is scientifically unjustified. Avian toxicity data are used in the assessment of secondary poisoning risks in aquatic and terrestrial food chains. Secondary poisoning concerns the potential toxic impact of a substance on a predatory bird or mammal following ingestion of prey items (i.e. fish and earthworms) that contain the chemical. Accumulation of chemicals through the food chain may follow many different pathways along different trophic levels. An assessment is solely required for substances indicating a bioaccumulation potential (ECHA, R.7c, 2008). Since the BCF values of the cresols (exp. BCF (o-cresol) = 10.7, exp. BCF (m-cresol) = 20) do not indicate a significant potential for bioaccumulation, no adverse effects on birds due to bioaccumulation in food chains is expected. Furthermore, biodegradability of the cresol isomers strongly determines the ability to bioaccumulate in organisms. As o-cresol, m-cresol, and p-cresol are readily biodegradable no risk of bioaccumulation arises. Based on these properties no adverse effects on birds due to bioaccumulation in food chains are expected and there is no need for testing.