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EC number: 284-892-9
CAS number: 84989-04-8
The fraction of tar acid rich in 3- and 4-methylphenol, recovered by distillation of low-temperature coal tar crude tar acids.
RS-Freetext:All animals showed signs of intoxication including hypoactivity, tremor,
convulsion, salivation, dyspnea, prostration within 4 hours post dosing
and from 100 mg onwards animals died.mortality occurred within 4 hours post dosing;68 mg/kg bw: no deaths but signs of intoxication; recovery within 2 days100 mg/kg bw: mortality: 2/5; survivors recovered within 4 days 147 mg/kg bw: mortality: 3/5; surviors recovered within 6 days215 mg/kg bw: mortality: 5/5At autopsy, survivors showed no significant findings, decedents showed
hemorrhage of gastrointestinal tract, hyperemia of liver, kidney and lungs
To determine LD50 -value 5 male rats/dose received single oral doses of
68, 100, 147, 215 mg/kg bw by gavage and were observed for symptoms and
mortality for up to 10 -14 days. Suvivors and decedents were examined
afterwards by gross autopsy:
LD50 was determined 121 mg/kg bw (Industrial Bio-test Laboratories 1969)
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