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EC number: 284-892-9
CAS number: 84989-04-8
The fraction of tar acid rich in 3- and 4-methylphenol, recovered by distillation of low-temperature coal tar crude tar acids.
m-cresol: EC50 (14 d) = 233 mg/kg d.w. standard soil on Lactuca sativa (OECD TG 208)o-cresol: EC50 (14 d) > 242 mg/kg d.w. standard soil on Lactica sativa (OECD TG 208)
o-cresol and m-cresol
The toxicity of o-cresol and m-cresol
to lettuce (Lactuca sativa) was
examined by Hulzebos (1993) according to OECD guideline 208. The organic
matter of the two soil types used in the experiment was given to range
between 1.4% and 1.8%. The weight of the above-ground biomass was
measured after 7 and 14 days. After an exposure period of 14 days an EC50
of >100 mg/kg dw soil was obtained for o-cresol and an EC50 of 96
mg/kg dw soil was obtained for m-cresol. According to TGD (EU 2003)
these values were normalised to a standard soil containing 3.4% of
organic matter, resulting in a corrected EC50 of >242 mg/kg for o-cresol
and a corrected EC50 of 233 mg/kg for m-cresol. The authors state that
during the test period, the concentrations of most phenols in soil
dropped to less than 20% of the initial concentrations.
The effect of p-cresol on the
germination of lettuce fruit (Lactuca sativa) was tested under
laboratory conditions (Reynolds, 1978). After an exposure period of 72 h
an EC50 of 122 mg/L was determined.
The scope of the terrestrial effects
assessment under the adopted REACH regulation is restricted to soil
organisms in a narrow sense and does not actually include adverse
effects on soil functions that are only indirectly linked to the biota
in soils. This test was designed assessing the influence of p-cresol on
germination and growth on moist filter paper or agar treated with the
substance. As no soil was used standardisation of soil effect data to
given soil parameters is not possible. Further, converting the results
to an appropriate dimension is not applicable. Therefore the result
should not be used for the hazard assessment. Nevertheless, the obtained
effect values indicate that p-cresol is of low toxicity to terrestrial
long-term toxicity to terrestrial
Long-term toxicity tests on plants are
not available. Based on the exposure assessment there is no unacceptable
risk of cresols to the soil ((PEC/PNEC < 1) and thus, long-term studies
on terrestrial plants do not need to be conducted.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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