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EC number: 202-607-8
CAS number: 97-77-8
Disulfiram is not expected to be persistent in soil (DT50 < 10 days).
No data on biodegradation of disulfiram in
soil (CAS No. 97 -77 -8) were available. Therefore, a conclusion based
on data from an analogue substance had
to be drawn. Biodegradation of tetramethylthiuram disulfide (CAS
No.137-26-8), substance structurally and composition related to
tetraethylthiuram disulfide, was investigated in two studies.In
the key study (Nag and Regis, 2000), conducted according to Comission
Directive 95/36/EC, and EU Method C.23: Aerobic and Anaerobic
Transformation in Soil under GLP conditions, the degradation rate of14C-thiram
was investigated in three european soils at 20°C plus an additional one
at 10°C, for 120 days.14C-thiram degraded rapidly in all
three soils, obtaining half-lives between 3.7 and 9.8 days, and being
ultimately mineralised to CO2. Similar
results were observed in the supporting study, where rapid degradation
of 14C-thiram took place in the soil tested (mainly due to
mineralisation), with a half-life of 2 days.
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