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Environmental fate & pathways

Adsorption / desorption

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Description of key information

Disulfiram shows potential for adsorption to the soil (log Koc of 3.3 (sandy loam) to 4.4 (loamy sand) L/kg).

Key value for chemical safety assessment

Additional information

No data on the adsorption/desorption potential of disulfiram (CAS No. 97-77-8) were available. Therefore, a conclusion based on data from an analogue substance had to be drawn. The adsorption potential of tetramethylthiuram disulfide (CAS No. 137-26-8), substance structurally and composition related to tetraethylthiuram disulfide, was investigated in a study.This test was conducted according to OECD Guideline No.106: Adsorption/Desorption using a Batch Equilibrium Method (2000) and EPA’s Pesticide Assessment Guidelines, CFR 40, Subdivision 163-1 (1982) under GLP conditions.14C-thiram was tested in 4 soil types obtaining log Koc values of 3.3 (sandy loam), 4.4 (loamy sand), 3.8 (silt loam) and 4.1 L/kg (loam).

The results from the KOCWIN v2.00 show that the predicted log Koc values for disulfiram are within the range obtained in the experimental study with the analogue substance.