Registration Dossier

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

No data on biodegradation of disulfiram were available. Therefore, conclusions for this section had to be drawn based on biodegradation data from the analogue substance, tetramethylthiuram disulfide (CAS No. 137-26-8). In view of these results, disulfiram can be considered as not readily biodegradable. This substance is expected to be rapidly degraded into several minor metabolites and ultimately mineralised to CO2 in water/sediment and soil systems (half-lives < 2 days and < 10 days respectively), and therefore it will not tend to persist in the environment.