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Ecotoxicological information

Short-term toxicity to fish

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Description of key information

LC50 (96h) = 0.067 mg/L (Lepomis macrochirus)

Key value for chemical safety assessment

Additional information

The acute toxicity of disulfiram (CAS No. 97-77-8) to fish species was investigated in two studies. McAllister and Cohle (1983; key study) tested the effects of this substance on Lepomis macrochirus, following US EPA-660/3-75-009 Guideline, Methods for Acute Toxicity Tests with Fish, Macroinvertebrates and Amphibians (1975), under GLP conditions. After 96 hours of exposure, lethal and sublethal effects were observed, resulting in a LC50 = 0.067 mg/L. An additional test (McAllister and Cohle, 1983; Balk, 1991) conducted with another freshwater fish species reported a 96h-LC50 of 0.22 mg/L.