Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 201-549-0 | CAS number: 84-65-1
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1974-1975
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: US study, brief summary report available
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 975
- Report date:
- 1975
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- The dust was generated by passing a stream of clean, dry air (-40°C dew-point) through a Ferris wheel generator containing the undiluted test material and into the test material. 4 hours exposure followed by 14 days observation period.
- GLP compliance:
- not specified
- Test type:
- standard acute method
- Limit test:
- no
Test material
- Reference substance name:
- Anthraquinone
- EC Number:
- 201-549-0
- EC Name:
- Anthraquinone
- Cas Number:
- 84-65-1
- Molecular formula:
- C14H8O2
- IUPAC Name:
- 9,10-dihydroanthracene-9,10-dione
- Details on test material:
- A.Q. Rec. Dry, 234/74
Constituent 1
Test animals
- Species:
- rat
- Strain:
- other: BLU: (LE)
- Sex:
- male/female
Administration / exposure
- Route of administration:
- inhalation: dust
- Type of inhalation exposure:
- whole body
- Vehicle:
- clean air
- Analytical verification of test atmosphere concentrations:
- not specified
- Duration of exposure:
- ca. 4 h
- Concentrations:
- 244,0 mg/m3 air (maximum attainable concentration)
- No. of animals per sex per dose:
- 5
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LC50
- Effect level:
- >= 244 mg/m³ air
- Based on:
- not specified
- Exp. duration:
- 4 h
- Mortality:
- no
- Clinical signs:
- other: There were no untoward reactions during exposure or the 14-day observation period which followed.
- Body weight:
- The average two-week body weight gains were within the normal limits.
- Gross pathology:
- Necropsy, performed on all rats at the end of observation period, did not reveal any gross pathologic alterations.
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: not specified
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
