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EC number: 201-549-0
CAS number: 84-65-1
Eastern oysters (Crassostrea
virginica) were continuously exposed to nominal concentration of 10
and 0.75 µg/L of Anthraquinone in seawater for 17 days after which
36 oysters from each exposure level were transfer to separate
aquaria containing flowing uncontaminated seawater for a 14-day
depuration period. The concentration of Anthraquinone in the
exposure test solutions and oyster tissues were monitored on day 0
(water only) 1, 3, 7, 10, 14 and 17 of the exposure period and days
1, 3, 7 and 14 of the depuration period.
Radiometric analysis of water and
oysters tissues received the following:
1.The concentration of aqueous14C
residues in the exposure system remains relatively constant at both
treatment levels throughout the 17 -day exposure period. Result of
these analyses established mean measured exposure concentrations
(standard deviations) of 7.1 (+/-0.4) and 0.78 (+/-0.05) µg/L
Anthraquinone (Day 0 -17). Throughout the 14 day depuration period,
-residues present in the water of the depuration aquaria for both
treatment levels (10 and 0.75 µg/L, nominal) remain below the limits
of radiometric detection (2.0 and 0.19 µ g/L, respectively).
2. The concentration of14C
-residues in the tissue of oysters exposed to Anthraquinone at both
treatment level, reached steady state by day 1 of the exposure
period. The mean (95% confidence interval) steady-state
bioconcentration factor (BCF) for14C
-residues in the tissues of oyster exposed to 7.1and 0.78 µg/L
Anthraquinone (Day 1 -17) were 140X (90X - 190X) and 110X (94X -
130X) respectively. Model calculation based on mean measured
concentration of 7.1 and 0.78 µg/L Anthraquinone in the test
solutions and corresponding concentration of14C
-residues in the tissue of the exposed oysters predict a
bioconcentration factor for Anthraquinone in oysters tissue was
independent of the exposure concentration.
3. Continued elimination of14C
-residues from oysters, after exposure to both 7.1 and 0.78 µg/L
Anthraquinone, was observed throughout the depuration period.
Half-life (50% elimination) of the14C
residues present in the oysters tissue during steady state (exposure
days 1 -14) occur during the firs 24 hours of the depuration period.
After 14 days depuration, 93% and 87% elimination of14C
-residues present during steady-state had been achieved in oysters
exposed to 7.1 and 0.78 µg/L Anthraquinone respectively.
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