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Toxicological information

Acute Toxicity: other routes

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Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Test method and results insufficient described

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1982
Report Date:
1982

Materials and methods

Principles of method if other than guideline:
The intraperitoneal LD50 (24 hours) was determined on male NMRI mice in a pre-test for a micronuleus test
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent
Test material form:
other: liquid
Details on test material:
3-chloroaniline ca. 98% - EGA Chemie

Test animals

Species:
mouse
Strain:
NMRI
Sex:
male

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
not specified
Doses:
no data
No. of animals per sex per dose:
no data
Control animals:
not specified

Results and discussion

Effect levels
Sex:
male
Dose descriptor:
LD50
Effect level:
216 mg/kg bw
Based on:
test mat.

Any other information on results incl. tables

The intraperitoneal LD50 = 216 mg/kg bw (confidence level: 137 - 343 mg/kg bw)

Applicant's summary and conclusion

Executive summary:

The intraperitoneal LD50 (24 hours) was determined on male NMRI mice in a pre-test for a micronuleus test. A LD50 = 216 mg/kg bw was found.