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Toxicological information

Acute Toxicity: inhalation

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Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: secondary literature

Data source

Reference
Reference Type:
review article or handbook
Title:
Toxicometric parameters of industrial toxic chemicals under single exposure
Author:
Izmerov NF, Sanotsky IV, Sidorov KK
Year:
1982
Bibliographic source:
Centre of International Projects GKNT Moscow 1982 - English-language edition UNEP

Materials and methods

Principles of method if other than guideline:
Determination of LC50 in mice after inhalation
GLP compliance:
no
Test type:
other: no data

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent
Test material form:
other: liquid
Details on test material:
no data

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
inhalation
Type of inhalation exposure:
not specified
Vehicle:
not specified
Analytical verification of test atmosphere concentrations:
not specified
Duration of exposure:
4 h
Concentrations:
no data
No. of animals per sex per dose:
no data
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LC50
Effect level:
550 mg/m³ air
Based on:
not specified
Exp. duration:
4 h

Any other information on results incl. tables

no data

Applicant's summary and conclusion

Executive summary:

The inhalation LC50(mouse) of m-chloroaniline is 550 mg/m³