Registration Dossier

Administrative data

Endpoint:
short-term toxicity to birds: acute oral toxicity test
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Reliable source. Study performed with acceptable restrictions.

Data source

Reference
Reference Type:
publication
Title:
The acute Oral Toxicity, Repellency, and Hazard Potential of 998 Chemicals to One or More Species of Wild and Domestic Birds.
Author:
Schafer, E. W. et al.
Year:
1983
Bibliographic source:
Arch. Environm. Contam. Toxicol. 12, 355 - 382 (1983)

Materials and methods

GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
other: liquid
Details on test material:
- Purity not reported
- Empirical formula: C6H6ClN
- Molecular mass: 127.58 g/mole
Dose method:
gavage

Test organisms

Test organisms (species):
other: Redwiged blackbird, Starling and Coturnix

Results and discussion

Effect levelsopen allclose all
Duration (if not bolus):
2 wk
Dose descriptor:
other: R50
Effect level:
> 1 other: %
Conc. / dose based on:
test mat.
Basis for effect:
mortality
Remarks on result:
other: Redwinged blackbird
Duration (if not bolus):
2 wk
Dose descriptor:
LD50
Effect level:
> 1 000 other: mg/kg
Conc. / dose based on:
test mat.
Basis for effect:
mortality
Remarks on result:
other: Starling
Duration (if not bolus):
2 wk
Dose descriptor:
LD50
Effect level:
422 other: mg/kg
Conc. / dose based on:
test mat.
Basis for effect:
mortality
Remarks on result:
other: Coturnix
Repellency factors (if applicable):
Redwinged blackbird: R50 = > 76.9 mg/kg
Further details on results:
The test period was during to 2 - 6 weeks for all species.

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Conclusions:
The acute oral toxicity of birds were determined to three species during from 2 to 6 weeks. The redwinged blackbird showed a R50 (repellency) of >1.00 % or > 76.9 mg/kg. The starling showed a LD50 of > 1000 mg/kg and the coturnix a LD50 of 422 mg/kg.
Executive summary:

The acute oral toxicity of birds were determined to three species during from 2 to 6 weeks. The redwinged blackbird showed a R50 (repellency) of >1.00 % or > 76.9 mg/kg. The starling showed a LD50 of > 1000 mg/kg and the coturnix a LD50 of 422 mg/k