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EC number: 204-000-3
CAS number: 112-72-1
Dodecan-1-ol has been tested for potential
reproductive toxicity in a combined repeat dose
reproductive/developmental toxicity screening study in rats conducted
according to the draft OECD guideline 422 and in compliance with GLP.
The materials were administered to male and female rats via the diet at
concentrations up to 30,000 ppm (2000 mg/kg bw/day) during pre-mating,
mating and gestation. Pregnancy rates, uterine parameters, time to
pregnancy and gestation length indicated that fertility was not affected
by exposure to octadecan-1-ol. There were no microscopic changes
observed in the reproductive organs.
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