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EC number: 204-000-3
CAS number: 112-72-1
Table 1. Summary of findings.
Toxicity to aquatic algae: 96 h EL50 and EL10 >LoS (>Limit of
Solubility) for the effects of the test substance on growth rate of
A 96 h EL50 of >10 mg/l has been determined for the effect of
tetradecanol on growth rate and biomass of Scenedesmus subspicatus (new
name: Desmodesmus subspicatus), and an ErL10 of 2.9
mg/l has been determined for the effect of tetradecanol on growth rate
of Scenedesmus subspicatus (new name: Desmodesmus subspicatus),
based on nominal concentrations [Henkel KGaA, 1992].
The solubility of tetradecanol is approximately 0.1-0.4 mg/l. The dose
response was above the solubility, which suggests the possibility of
physical fouling, and as no effects were observed on growth rate at 1
mg/l, it may be concluded that tetradecanol is not toxic at its limit of
The study reflects the lowest reliable value that is available for this
Additionally, supporting data have been read-across from the mixture,
Alcohols C14-C15 (CAS 75782-87-5):
96-h ErL50 22-46 mg/l for effects on growth rate, and NOEL
4.6 mg/l for effects on growth rate and biomass (WAF) (>LoS) of Raphidocelis
subcapitata (new name: Pseudokirchneriella subcapitata)
[Shell Research, 2000].
These results support the view that C14 is non-toxic at the limit of
Discussion of trends in the Category of C6-24 linear and
essentially-linear aliphatic alcohols:
The data for single carbon chain length LCAAs show toxicity to increase
from an ErC50 of 80 mg/L for C6 to 0.33 mg/L for C12. The C14
and C16 LCAAs were not toxic to algae, indicating a toxicity cut-off at
C14 and above. Two of the studies determined NOECs that are suitable for
assessing long-term toxicity. A NOEC of 11 mg/L has been reported for
hexan-1-ol based on measured exposure concentrations. A test with
dodecanol resulted in a 72-h EC0 (equivalent to a NOEC) value
of 0.085 mg/L.
Other algal studies used a WAF methodology and/or used test
concentrations greater than the limit of water solubility and/or did not
report a NOEC or equivalent statistic.
The data for mixed carbon chain length LCAAs (commercial products)
shows that substances containing LCAAs with carbon numbers in the ranges
of C7-9 to C12-15 exerted toxicity at concentrations of between 3.1 and
0.043-0.092 mg/L. At these concentrations all the constituents are
likely to have been fully dissolved. For the C12-18 and C14-15
multi-constituent substances there was evidence of toxic effects in
tests conducted on water-accommodated fractions prepared at loading
rates that will have exceeded the solubility of some constituents.
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