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EC number: 204-000-3
CAS number: 112-72-1
(7 d) NOEC 1.0 mg/L
In accordance with Column 2 of REACH Annex IX, the study does not need
to be conducted.
A comprehensive long-term toxicity study is not available, but a shorter
version of an early life stage toxicity test, commonly used as an early
screening method, with the test substance is available (see section
6.1.1 Pickering et al. 1996). A 7 day NOEC value equivalent to
1.5 mg/L was determined for the effects of the test substance on
survival and growth of the larvae of the freshwater fish Pimephales
promelas. The study reflects the only reliable value that is
available for this endpoint. However, a longer term toxicity study has
Testing for long term toxicity to fish is not considered necessary
A recent long-term toxicity test has been carried out with decan-1-ol.
There was intensive method development to attempt to overcome very
significant biodegradation losses of substance in the test system.
Whilst testing is not technically impossible, it requires very
significant efforts which are disproportionate to the need for data.
The freshwater PNEC has been derived from the data with long-term
toxicity to invertebrates (Daphnia). There are three available
NOEC values for toxicity to fish across the LCAAs category. These NOEC
values indicate that they are in a similar range to the NOEC values that
have been determined for long-term toxicity to invertebrates. In
addition, the available short-term data set demonstrates that all
trophic levels are of similar sensitivity.
The risk characterisation ratios (RCRs) based on the PNECfreshwater
derived from the long-term toxicity to invertebrates data are <1,
therefore no further testing is considered necessary.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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