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EC number: 204-000-3
CAS number: 112-72-1
RESULTS OF RANGE FINDING STUDY:
Following intradermal injection, skin irritation was seen at concentrations of 10% and 5% persisting for 72 hours
but less marked at the lower concentration. The 3% concentration showed evidence of irritation at 24 hours in oneanimal only. Lower concentrations from 0.1 -1% showed no irritation. Following topical application slight
irritation was seen in 2/4 animals at 50% only.
TEST: There was no evidence of sensitisation in any of the test or control animals at either challenge concentration
Table 1. Summary of the delayed
contact hypersensitivity study of KALCOL 4098 in female guinea-pigs
Number of animals showing positive reaction/Total number of animals
24 hrs after challenge
48 hrs after challenge
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