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EC number: 204-826-4
CAS number: 127-19-5
Sperm abnormality tests were performed in male B6C3F1 mice after in vivo
exposure to 20 or 700 ppm of the test substance for 7 hours/day for 5
days (non-guideline, GLP not specified). Mice were exposed via whole
body exposure. Mice were killed five weeks after the last day of dosing.
Sperm was placed in the categories "normal" and "abnormal" whereas for
abnormal the subcategories "hook upturned or elongated", "banana-shaped"
or "amorphous" head, "abnormal tail", and "miscellaneous" were chosen.
There were no increases in the frequencies of abnormal sperm in any of
the categories examined. There were no sperm abnormalities in male
B6C3F1 mice after repeated exposure to 700 ppm (2500 mg/m³).
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