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EC number: 204-826-4
CAS number: 127-19-5
Table 1: Mortality in male and female ChR-CD rats after
gavage within the post exposure observation period of 14 days
of 10 ChR-CD rats per sex per dose were gavaged with 4500 - 6500 mg/kg
bw (4 dose levels per sex). The post exposure observation period was 2
rats died at a dose level >=5500 mg/kg bw and no mortality was found at
5000 mg/kg bw. In females even at the low dose level lethal effects were
signs like belly-to-cage posture, wet and/or stained mouth, nose and
perineal area, half closed eyes, diarrhea, tremors, piloerection,
pallor, prostration, lethargy, chromodacryorrhea, and cyanosis were
In male ChR-CD rats the oral LD50 was 5810 mg/kg bw and in females 4930
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