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EC number: 204-826-4
CAS number: 127-19-5
The inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriately low concentrations.
The toxicity of N,N-dimethylacetamide
(CAS 127-19-5) to microorganisms was investigated in a study conducted
equivalent to OECD 209, but using activated sludge from an industrial
wwtp. The 30-min EC10 was determined to be greater than 1995 mg/L based
on the respiration rate (BASF AG, 1980; report no. 1168; cited in OECD
SIDS, 2001). These data were selected as key data for the chemical
A further study was conducted with the
single species Pseudomonas putida according to DIN 38412-27. A 16-h LOEC
of 4850 mg/L could be determined, supporting the data of the key study.
As the original report of this study is not available, the exposure
duration was assumed to be 16 hours (BASF AG, 1986; report no. 312186;
cited in OECD SIDS, 2001).
Based on the available experimental
data, N,N-dimethylacetamide (CAS 127-19-5) is concluded to not inhibit
the degradation activity of activated sludge when introduced in
appropriately low concentrations.
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