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EC number: 204-826-4
CAS number: 127-19-5
With high probability acutely not harmful to aquatic invertebrates.
Considering the toxicity of
N,N-dimethylacetamide to aquatic invertebrates there are experimental
data from two studies for each, the freshwater and marine compartment
- In a static test conducted according
to EU method C.2., using D. magna as test organism, a 48-h EC50 of >500
mg/L was determined, based on nominal test concentrations (BASF AG,
1988; report no. 1/1021/2/88-1021/88). These data were selected as
- In a supporting acute toxicity test
(guideline not specified in study report) with D. magna as test
organism, the 48-h EC50 was >1000 g/L (nominal, Adema, 1987; cited in
OECD SIDS, 2001).
- A semi-static acute toxicity test
(guideline not specified in study report) was conducted using
Americamysis bahia (former: Mysidopsis bahia) as test organism. Based on
nominal test concentrations the 96-h EC50 was found to be 966 mg/L
(Adema, 1987; cited in OECD SIDS, 2001). These data were selected as
- In a further acute toxicity test
conducted under marine conditions (guideline not specified in study
report) the test organism was chaetogammarus marinus. After an exposure
period of 96 h the EC50 was determined to be >1000 mg/L, supporting the
results of the marine key study (Adema, 1987; cited in OECD SIDS, 2001).
In conclusion, the substance is assessed
to be with probability acutely not harmful to aquatic invertebrates.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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