Registration Dossier

Classification & Labelling & PBT assessment

PBT assessment

Currently viewing:

Administrative data

PBT assessment: overall result

PBT status:
the substance is not PBT / vPvB
Justification:

N,N-dimethylacetamide (CAS 127-19-5) is readily biodegradable according to OECD criteria, therefore the substance is not P or vP. The substance does not accumulate in organisms, based on a measured Log Kow of -0.77 and is, therefore, not B or vB. The substance is also not T since the lowest available chronic value is > 0.01 mg/L (algae: 72-h NOErC ≥ 500 mg/L). However, due to effects on reproduction of mammals (category repr. 1B; H360D) the substance has to be regarded as toxic.

 

In summary, the substance does not fulfill the PBT and vPvB criteria.