Registration Dossier

Administrative data

Endpoint:
additional ecotoxicological information
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: The study is a public domain review of other public domain ecotoxicology studies. Information on the methods used for ecotoxicology testing are not presented in the paper and as such the reliability cannot be assessed fully.

Data source

Reference
Reference Type:
publication
Title:
Hazardous and noxious substances (HNS) in the marine environment: prioritizing HNS that pose major risk in a European context
Author:
Neuparth, T., Moreira, S., Santos, M., Reis-Henriques, M.
Year:
2011
Bibliographic source:
Marine Pollution Bulletin (62), 21-28

Materials and methods

Test guideline
Qualifier:
no guideline required
Principles of method if other than guideline:
Review of data available from other published studies.
GLP compliance:
no
Type of study / information:
The study aims to select and prioritize substances based on the risk they are likely to cause if spilled into the marine environment. In order to do this the study takes into account information on the volumes transported, reported incidents, physico-chemical properties and toxicity to marine organisms. Acrylonitrile is among the substances considered and data is included for toxicity to marine organisms.

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Any other information on results incl. tables

Table 1: Summary of ecotoxicological results for acrylonitrile

Test species

Test type

Aquatic medium

Salinity (%)/ temperature (oC

Age/size

Effect concentration (mg/L)

Effect measured

Crustacea

Artemia salina

Acute

Seawater

NR/25

Nauplii

14.34 (48h EC50)

Survival

Crustacea

Crangon franciscorum

Acute

Seawater

NR

NR

10-33 (24h LC50)

Survival

Fish

Lagodon rhomboids

Acute

Seawater

NR/ 13.7-20.4

NR

24.5 (24h LC50)

Survival

Crustacea

Daphnia magna

Chronic

Freshwater

24

Neonates <24h

1 (21 day LOEC)

0.5 ( 21 day NOEC)

Reproduction

Fish

Cyprinus carpio

Chronic

Freshwater

22

Embryo larva

3.2 (7 day LOEC)

1.6 (7 day NOEC)

Survival

Applicant's summary and conclusion

Conclusions:
Acute and chronic values are presented for a number of freshwater and marine species. The lowest acute acute value was for Artemia salina with a 48-hour EC50 of 14.34 mg/L. The lowest chronic endpoint is that of Daphnia magna, with a 21-day NOEC of 0.5 mg/L.
Executive summary:

A review was conducted of public domain data for the aquatic toxicity of acrylonitrile in order to assess the risk to the marine environment. Studies for both freshwater and marine species were presented.

The lowest acute acute value was for Artemia salina with a 48-hour EC50 of 14.34 mg/L. The lowest chronic endpoint is that of Daphnia magna, with a 21-day NOEC of 0.5 mg/L.