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Ecotoxicological information

Toxicity to microorganisms

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Description of key information

The data overall suggest that acrylonitrile, while having an initial inhibitory effect on microorganisms, is of relatively low toxicity at concentrations below 100 mg/l.

Key value for chemical safety assessment

EC10 or NOEC for microorganisms:
50 mg/L

Additional information

Results of biodegradation testing shows that acrylonitrile has an initial inhibitory effect on non-acclimated microorganisms, but following acclimation EC50s for microorganisms are generally in excess of 100 mg/l. The results of microbial toxicity tests and biodegradation studies on acrylonitrile indicate a potential effect on microorganisms in wastewater treatment plants, at least on start-up. The reported EC50s range from 1- >1,800 mg/l. Results with acclimated microbial populations and in simulation tests have indicated no inhibitory effect of acrylonitrile at levels as high as 200 mg/l, and a conservative estimate of 50 mg/l for a NOEC in such populations has been assumed (EU RAR 2004).