Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-466-5
CAS number: 107-13-1
Although the validity of the prolonged toxicity study in Daphnia
by Tong et al (1996b) can be questioned in respect of reaching
the conclusion that there are three valid long-term NOECs, the NOEC
determined in the study is consistent with those established in the fish
early life study and the algal toxicity study. A PNEC is derived using
an assessment factor of 10. Applying this factor to the NOEC derived
from the fish early life stage toxicity test in Pimephales promelas gives
a PNEC of 17 μg/L.
The results of microbial toxicity tests and biodegradation studies on
acrylonitrile indicate a potential effect on microorganisms in
wastewater treatment plants, at least on start-up. The reported EC50s
range from 1- >1,800 mg/L. Results with acclimated microbial populations
and in simulation tests have indicated no inhibitory effect of
acrylonitrile at levels as high as 200 mg/L, and a conservative estimate
of 50 mg/L for a NOEC in such populations has been assumed (EU RAR
2004). Application of a factor of 10 to this NOEC derives a PNEC of 5
mg/L for microorganisms in acclimated wastewater treatment plants
handling acrylonitrile on a continuous basis. A factor of 10 is
considered justified given the relatively large body of data on
microbial toxicity of acrylonitrile.
No data are available; studies for this endpoint are waived on the basis
of exposure. The PNEC sediment is of 0.0188 mg/kg is derived using the
equilibrium partitioning method (EPM) based on the PNEC water of 0.017
A PNEC for soil of 0.00268 mg/kg (based on PNEC (aquatic) of 17 μg/L)
can be derived using the equilibrium partition approach.
Acrylonitrile is listed in Annex VI of the CLP Regulation (EC)
1272/2008 with classification as H411, Aquatic Chronic Category 2. No
new data are available, therefore no change to this classification is
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
På den här webbplatsen används kakor. Syftet är att optimera din upplevelse av den.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again