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EC number: 202-448-4
CAS number: 95-76-1
Löser, E, 1981, study report, Bayer AG
In this study 3,4-dichloroaniline was administered to groups of 10 male
Wistar TNO W74 rats by oral gavage in doses of 0.3,0.5, 0.6, 0.7 or 0.8
g/kg body weight. Clinical signs of toxicity and mortality were
documented. In the 0.3 g/kg bw group no toxixity was evident. All other
groups showed increasing signs of toxicity including diarrhoea,
chromodakryorrhoe, bloody snout, face down position, reduced spontaneous
activity, narkosis, paralysis of hint extremities. Dead animals were
found in those groups on the second or third day post-application. The
calculated LD50 was 0.57 g/kg bw.
According to this study 3,4-dichloroaniline should be classified as
harmful if swallowed.
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