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Ecotoxicological information

Additional ecotoxological information

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Administrative data

Endpoint:
additional ecotoxicological information
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: only results in EU risk assessment

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Toxikokinetik von 3,4-Dichloranilin beim dreistachligen Stichling (Gasterosteus aculeatus) unter besonderer Berücksichtigung der Fortpflanzungsphysiologie.
Author:
Allner B (1997)
Year:
1997
Bibliographic source:
Dissertation am Fachbereich Biologie der Johann Gutenberg-Universität in Mainz.
Reference Type:
secondary source
Title:
3,4-dichloroaniline (3,4-DCA)
Author:
EU-Risk Assessment Report
Year:
2006
Bibliographic source:
EUR 22235 EN; ISSN 1018-5593

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
no data
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Any other information on results incl. tables

3,4-DCA is known to have endocrine effects on fish. It could be shown (Allner, 1997) that 3,4-DCA causes lowered androgen synthesis at tested concentrations of 200 and 400 µg/l in breeding male Sticklebacks (Gasterosteus aculeatus). The changes in androgen metabolism are accompanied by changes in the secondary sex characters at concentration of 100, 200 und 400 µg/l. The splendid colour typical of breeding males become regressive and courtship behavior occurs no longer.

Applicant's summary and conclusion