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Ecotoxicological information

Biotransformation and kinetics

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Administrative data

Endpoint:
biotransformation and kinetics
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Acceptable publication

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Reductive dehalogenation of dichloroanilines by anaerobic microorganisms in fresh and dichlorophenol acclimated pond sediment.
Author:
Struijs, Rogers
Year:
1989
Bibliographic source:
Appl. Environ. Microbiol. 55,|2527-2531
Reference Type:
review article or handbook
Title:
2,4-Dichloranilin; 2,5-Dichloranilin; 3,4-Dichloranilin
Author:
Beratergremium für umweltrelevante Altstoffe (BUA)
Year:
1994
Bibliographic source:
Wissenschaftliche Verlagsgesellschaft, BUA report 140
Reference Type:
secondary source
Title:
3,4-dichloroaniline (3,4-DCA)
Author:
EU-Risk Assessment Report
Year:
2006
Bibliographic source:
EUR 22235 EN; ISSN 1018-5593

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
no data
GLP compliance:
not specified
Type of medium:
other: Seesediment, adaptiert

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Identity of transformation productsopen allclose all
No.:
#1
Reference
Reference substance name:
Unnamed
Inventory number:
InventoryMultipleMappingImpl [inventoryEntryValue=EC 203-581-0]
IUPAC name:
3-chloroaniline
CAS number:
108-42-9
No.:
#2
Reference
Reference substance name:
Unnamed
Inventory number:
InventoryMultipleMappingImpl [inventoryEntryValue=EC 203-401-0]
IUPAC name:
4-chloroaniline
CAS number:
106-47-8

Any other information on results incl. tables

Sediment

Biodegradation tests under anaerobic conditions with fresh-water-sediment and pond-sediment

indicate primary degradation through reductive dechlorination to monochloroaniline (3- and

4-chloroaniline) only. The dechlorination started after 20 days of incubation in unacclimated

sediments. Approximately 90% of the 3,4-DCA was dechlorinated within the next 40 days. After

60 days 44% of the 3,4-DCA was present as 3-chloroaniline and 33% as 4-chloroaniline. Further

degradation of the monochloroanilines was not observed in these studies. The

monochloroanilines, however, appeared to be resistant to further dechlorination (Struijs and

Rogers, 1989). No information on mineralisation is available.

Applicant's summary and conclusion