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Ecotoxicological information

Toxicity to birds

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Administrative data

Endpoint:
short-term toxicity to birds: acute oral toxicity test
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Information about test method are missing and only short-term investigation with birds determining the acute lethal effect after oral application is available. This study cannot be used for the assessment

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Arch. Environ. Contam. Toxicol. 12,|355-382
Author:
Schafer et al. (1983):
Year:
1983
Reference Type:
secondary source
Title:
3,4-dichloroaniline (3,4-DCA)
Author:
EU-Risk Assessment Report
Year:
2006
Bibliographic source:
EUR 22235 EN; ISSN 1018-5593
Reference Type:
review article or handbook
Title:
2,4-Dichloranilin; 2,5-Dichloranilin; 3,4-Dichloranilin
Author:
Beratergremium für umweltrelevante Altstoffe (BUA)
Year:
1994
Bibliographic source:
Wissenschaftliche Verlagsgesellschaft, BUA report 140

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Acute oral toxicology tests
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
3,4-dichloroaniline
EC Number:
202-448-4
EC Name:
3,4-dichloroaniline
Cas Number:
95-76-1
Molecular formula:
C6H5Cl2N
IUPAC Name:
3,4-dichloroaniline
Details on test material:
purity: no data

Test organisms

Test organisms (species):
other: other avian: Agelaius phoenicus

Results and discussion

Effect levelsopen allclose all
Duration (if not single dose):
18 h
Dose descriptor:
LD50
Effect level:
237 mg/kg bw
Basis for effect:
mortality
Dose descriptor:
other: R50
Effect level:
0.316 other: mg/0.1 g food
Conc. / dose based on:
test mat.
Basis for effect:
repellency
Remarks on result:
other: 1.58 mg/feeding
Dose descriptor:
other: R50
Effect level:
24.6 mg/kg bw
Conc. / dose based on:
test mat.
Basis for effect:
repellency
Remarks on result:
other: calculated value

Any other information on results incl. tables

For 3,4-DCA a short-term investigation with birds determining the acute lethal effect

after oral application is available. After 18 hours a LD50 of 237 mg/kg bw/day for Red-winged

Black birds were obtained. 3,4-DCA was usually dosed by gavage with solutions or suspensions

in propylene glycol (Schafer et al., 1983). This study cannot be used for the assessment.

Applicant's summary and conclusion

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