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Registration Dossier
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EC number: 202-448-4 | CAS number: 95-76-1
Sediment toxicity
Administrative data
- Endpoint:
- sediment toxicity: long-term
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Original paper not available but peer reviewed in EU Risk assessment.
Data source
Referenceopen allclose all
- Reference Type:
- secondary source
- Title:
- 3,4-dichloroaniline (3,4-DCA)
- Author:
- EU-Risk Assessment Report
- Year:
- 2 006
- Bibliographic source:
- EUR 22235 EN; ISSN 1018-5593
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 2 000
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- Long term test with Lumbriculus variegatus.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 3,4-dichloroaniline
- EC Number:
- 202-448-4
- EC Name:
- 3,4-dichloroaniline
- Cas Number:
- 95-76-1
- Molecular formula:
- C6H5Cl2N
- IUPAC Name:
- 3,4-dichloroaniline
Constituent 1
Test organisms
- Test organisms (species):
- Lumbriculus variegatus
Study design
- Study type:
- laboratory study
- Test type:
- not specified
- Water media type:
- freshwater
- Type of sediment:
- artificial sediment
- Limit test:
- no
Exposure duration
- Duration:
- 28 d
- Exposure phase:
- total exposure duration
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 25.2 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Duration:
- 14 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 5 mg/kg sediment dw
- Conc. based on:
- test mat.
- Basis for effect:
- reproduction
- Duration:
- 14 d
- Dose descriptor:
- LOEC
- Effect conc.:
- 25 mg/kg sediment dw
- Conc. based on:
- test mat.
- Basis for effect:
- reproduction
Any other information on results incl. tables
For Lumbriculus variegatus a NOEC of 5 mg/kg dw was found for the total number of worms. This can be seen as the endpoint
relevant for the assessment.
Applicant's summary and conclusion
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