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Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: secondary source

Data source

Reference
Reference Type:
review article or handbook
Title:
Toxicology of drugs and chemicals
Author:
Deichmann WB, Gerarde HW
Year:
1969
Bibliographic source:
Academic Press, New York and London

Materials and methods

Principles of method if other than guideline:
no data
GLP compliance:
no
Test type:
other: no data

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
no data

Test animals

Species:
other: rat, mouse, guinea pig
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
not specified
Doses:
no data
No. of animals per sex per dose:
no data
Control animals:
not specified

Results and discussion

Effect levels
Dose descriptor:
LD50
Effect level:
1 600 mg/kg bw
Remarks on result:
other: rat, mouse, guinea pig

Any other information on results incl. tables

The signs observed with this material are those of anesthesia in the larger doseages. The animals either die promptly from deep anesthesia or recover completely by the next day. In smaller dosages minimal or no signs are observed

Applicant's summary and conclusion

Interpretation of results:
harmful
Remarks:
Migrated information
Executive summary:

LD50(rat, mouse, guinea pig) = 1600 mg/kg bw.

The signs observed with this material are those of anesthesia in the larger doseages. The animals either die promptly from deep anesthesia or recover completely by the next day. In smaller dosages minimal or no signs are observed