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EC number: 201-114-5
CAS number: 78-40-0
In the present study, 12 organophosphate esters (OPEs) were analyzed in
human placenta for the first time to understand the accumulation
characteristics of OPE in placenta. TCEP was identified as the most
abundant OPE in the human placentas. The concentrations of the 9 most
frequently detected OPEs (Σ9OPEs) ranged from 34.4 to 862 ng/g lipid
weight (lw), with a median of 301 ng/g lw. Tri(2-chloroethyl) phosphate
(TCEP) was identified as the most abundant analog,with a median
concentration of 142 ng/g lw, followed by tributoxyethyl phosphate
(TBEP) and triphenyl phosphate (TPhP). Triphenyl phosphate (TEP) had a
median concentration of 10.2 ng/g lw.
The concentrations of OPE analogs were found to be independent of the
lipid content. No obvious association was observed between the total
accumulation level of OPEs in placenta and maternal characteristics such
as age, gestational age, previous gravidity, previous breast feeding
history, and food consumption habits.
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