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EC number: 201-114-5
CAS number: 78-40-0
The loss of the alkyl group in trialkyl phosphates is due both to
enzymic hydrolysis (P-O cleavage) and de-O-alkylation (C-O cleavage),
the latter being known to involve reduced gluthatione as acceptor.
32P-TEP is rapidly excreted as their metabolites by both rat and mouse
with 90% recovery of radioactive material in urine within 16 h and
nearly complete recovery over 96 h. Urine of rats and mice were examined
for metabolites of 32P-triethylphosphate. 32P-triethylposphate was
excreted by both species as 32-diethylphosphate. As a further metabolite
S-ethylcysteine was found. In neither case was the trialkyl-phosphate
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