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EC number: 214-604-9
CAS number: 1163-19-5
DecaBDE has negligible solubility in water
(<0.1 ug/L), and minimal partitioning to this media in the environment
is predicted. Aquatic organism toxicity is not expected. DecaBDE's
database is populated by studies having high no adverse effect levels.
For example, the mammalian repeated dose NOAEL is at least 1000 mg/kg
bw/d, and terrestrial and sediment studies reported even higher NOAELs.
The studies on which these NOAELs are based were performed using the
commercial DecaBDE product as test article, and, examined by default,
any impurities in the product and metabolites. The high NOAELs indicate
the BDE-209 congerner, impurities in the commercial product and/or
metabolites are not of concern. These impurities and possible
metabolites are captured in the PNEC for secondary poisoning (222 mg/kg
food), because the repeated dose NOAEL was used in its calculation.
DecaBDE is not toxic to the aquatic,
terrestrial and sediment organisms tested. It has little to no potential
for bioaccumulation, and recent work indicates doses above ca. 2 mg/kg
bw do not result in higher internal expsoures. Field studies have not
indicated a potential to biomagnify. A concern for possible secondary
poisoning from metabolites is not justified given the high NOAELs
(>=1000 mg/kg) in long term mammalian, terrestrial and sediment-dwelling
organisms. Speculation that DecaBDE may be metabolized to toxic
substances is not supported by DecaBDE's extensive database, which
includes lifetime mammalian studies.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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