Registration Dossier

Ecotoxicological information

Long-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
long-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1996-1997
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Study performed according to international guidelines and GLPs.

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Unnamed
Year:
2002
Reference Type:
study report
Title:
Unnamed
Year:
1997

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
EPA OPPTS 850.1300 (Daphnid Chronic Toxicity Test)
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
The commerical octabromodiphenyl ether was used as test article. In consultation with the UK, DecaBDE was not tested due to its extremely low water solubility (<0.1 ug/L) and difficult analysis.

Sampling and analysis

Analytical monitoring:
yes

Test solutions

Vehicle:
yes

Test organisms

Test organisms (species):
Daphnia magna

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
21 d
Post exposure observation period:
no

Test conditions

Hardness:
see EU RAR
Test temperature:
see EU RAR
pH:
see EU RAR
Dissolved oxygen:
see EU RAR
Salinity:
see EU RAR
Nominal and measured concentrations:
up to 2 ug/L (solubility limit for octabromodiphenyl ether)
Reference substance (positive control):
no

Results and discussion

Effect concentrations
Duration:
21 d
Dose descriptor:
NOEC
Effect conc.:
> 2 µg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
other: survival, reproduction, growth

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
DecaBDE is not expected to be chronically toxic to Daphnia at the limit of its solubility.
Executive summary:

EU RAR DecaBDE, pg 92: "A long-term Daphnia test has been carried out using octabromodiphenyl ether. No effects on survival, reproduction or growth were seen over 21 days at concentrations up to 2 µg/l (solubility limit) (see the assessment of that substance for further details). Taken as a whole, it is clear that the aquatic toxicity and bioaccumulation potential of the polybrominated diphenyl ethers (penta-, octa- and decabromodiphenyl ether) decreases with increasing bromination and therefore it is unlikely that decabromodiphenyl ether will show any toxic effects to invertebrates at concentrations below its solubility limit."