Registration Dossier

Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Study was performed by Japan's Chemicals Inspection & Testing Institute, MITI, Tokyo. Cited in the 2002 EU RAR on DecaBDE.

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Biodegradation and Bioaccumulation Data of Existing Chemicals Based on the CSCL Japan
Author:
Anonymous
Year:
1992
Bibliographic source:
Eds. Chemical Inspection & Testing Insitute, Japan Chemical Industry Ecology-Toxicology & Information Center, Tokyo, Japan
Reference Type:
publication
Title:
Unnamed
Year:
2002

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: Japanese Industrial Standard JIS K 0102-1986-71 "Testing methods for industrial waste water"
Deviations:
no
Principles of method if other than guideline:
48 h acute toxicity test in the orange-red killifish. performed as a preliminary to fish bioaccumulation study.
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent

Sampling and analysis

Analytical monitoring:
no

Test solutions

Vehicle:
yes

Test organisms

Test organisms (species):
Oryzias latipes

Study design

Test type:
other: static or semi-static
Water media type:
freshwater
Limit test:
yes
Total exposure duration:
48 h
Post exposure observation period:
no

Test conditions

Hardness:
Met Ministry of Health and Welfare (Au 31, 1978) ordinance for total hardness.
Test temperature:
25 +- 2 degrees C
pH:
Met water quality criteria for fisheries (Shandanhozin Nihon Suisansigen Hogokyokai, March 1983)
Dissolved oxygen:
Met water quality criteria for fisheries (Shandanhozin Nihon Suisansigen Hogokyokai, March 1983)
Salinity:
freshwater derived from well at Kurume Research Laboratories, Kurume, Japan
Nominal and measured concentrations:
500 mg/L
Reference substance (positive control):
no

Results and discussion

Effect concentrations
Duration:
48 wk
Dose descriptor:
LC50
Effect conc.:
> 500 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
The 48 h LC50 for DecaBDE in the orange-red killifish was > 500 mg/L.
Executive summary:

The 48 h LC50 for DecaBDE in the orange-red killifish was > 500 mg/L.