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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Administrative data

Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Guideline study with slight modifications according to Van Leeuwen et al. (1985). Limited documentation.

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Unnamed
Year:
1982
Report date:
1982
Reference Type:
secondary source
Title:
European Union Risk Assessment Report, Nitrobenzene, CAS No: 98-95-3
Author:
European Chemicals Bureau
Year:
2007
Bibliographic source:
3rd Priority List, Volume: 77
Report date:
2007

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 201 (Alga, Growth Inhibition Test)
GLP compliance:
no
Remarks:
test prior to 1 June 2008

Test material

Constituent 1
Chemical structure
Reference substance name:
Nitrobenzene
EC Number:
202-716-0
EC Name:
Nitrobenzene
Cas Number:
98-95-3
Molecular formula:
C6H5NO2
IUPAC Name:
nitrobenzene
Details on test material:
- Analytical purity: No data about the degree of purity of the test substance were provided.
DMSO (purity 99%) was used as vehicle for the preparation of the stock solution.

Sampling and analysis

Analytical monitoring:
no

Test solutions

Vehicle:
yes

Test organisms

Test organisms (species):
Chlorella pyrenoidosa
Details on test organisms:
Growing Chlorella pyrenoidosa

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
96 h

Results and discussion

Effect concentrations
Duration:
96 h
Dose descriptor:
EC50
Effect conc.:
18 mg/L
Nominal / measured:
not specified
Conc. based on:
test mat.
Basis for effect:
growth rate

Applicant's summary and conclusion

Validity criteria fulfilled:
yes